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Catalyst dx analyzer

Manufactured by IDEXX
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Sourced in United States

The IDEXX Catalyst DX analyzer is a compact, automated in-house chemistry analyzer designed for veterinary practices. It performs a variety of diagnostic tests on small blood samples to aid in the assessment of animal health.

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Lab products found in correlation

Gwb axr320, by Aviva Systems Biology (1 mentions) Nbp2 60633, by Novus Biologicals (1 mentions) Procyte dx, by IDEXX (1 mentions) Procyte dx hematology analyzer, by IDEXX (1 mentions) Mouse ctni elisa kit, by Nanjing Jiancheng (1 mentions)

Close spelling variants of this product

Catalyst Dx Chemistry Analyzer system Catalyst Dx Chemistry Analyzer Catalyst Dx

8 protocols using catalyst dx analyzer

1

Serum Enzyme and Lipid Levels

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The levels of serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), triglyceride (TG) and cholesterol (Chol) were measured with IDEXX Catalyst Dx analyzer (IDEXX Laboratories, Westbrook, Maine).
Parker R., Kim S.J., Im G.Y., Nahas J., Dhesi B., Vergis N., Sinha A., Ghezzi A., Rink M.R., McCune A., Aithal G.P., Newsome P.N., Weston C.J., Holt A, & Gao B. (2019). Obesity in acute alcoholic hepatitis increases morbidity and mortality. EBioMedicine, 45, 511-518.
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2

Plasma Biomarker Quantification Protocol

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Whole blood was collected by cardiac puncture in EDTA-coated tubes. Plasma was collected by centrifugation at 3000g at 4°C for 15 minutes. Plasma was kept on ice or at –20°C for longer storage. ALT in the plasma samples was measured by using an IDEXX Catalyst DX analyzer (IDEXX Laboratories). Heme concentration in plasma was measured by the hemin colorimetric assay kit (GWB-AXR320, Genway Biotech). Hpx in plasma was measured by ELISA (NBP2-60633, Novus Biologicals).
Lee G.R., Gallo D., Alves de Souza R.W., Tiwari-Heckler S., Csizmadia E., Harbison J.D., Shankar S., Banner-Goodspeed V., Yaffe M.B., Longhi M.S., Hauser C.J, & Otterbein L.E. (2021). Trauma-induced heme release increases susceptibility to bacterial infection. JCI Insight, 6(20), e150813.
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3

Muscle Damage Biomarker Evaluation

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Serum creatine kinase (CK) and lactate dehydrogenase (LDH) were used for evaluation of muscle damage. Blood samples were collected at the indicated time points from the heart, immediately before induced death. Serum samples were analyzed on an IDEXX Catalyst DX analyzer (IDEXX Laboratories).
de Souza R.W., Gallo D., Lee G.R., Katsuyama E., Schaufler A., Weber J., Csizmadia E., Tsokos G.C., Koch L.G., Britton S.L., Wisløff U., Brum P.C, & Otterbein L.E. (2021). Skeletal muscle heme oxygenase-1 activity regulates aerobic capacity. Cell reports, 35(3), 109018.
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4

Muscle Damage Biomarker Evaluation

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Serum creatine kinase (CK) and lactate dehydrogenase (LDH) were used for evaluation of muscle damage. Blood samples were collected at the indicated time points from the heart, immediately before induced death. Serum samples were analyzed on an IDEXX Catalyst DX analyzer (IDEXX Laboratories).
de Souza R.W., Gallo D., Lee G.R., Katsuyama E., Schaufler A., Weber J., Csizmadia E., Tsokos G.C., Koch L.G., Britton S.L., Wisløff U., Brum P.C, & Otterbein L.E. (2021). Skeletal muscle heme oxygenase-1 activity regulates aerobic capacity. Cell reports, 35(3), 109018.
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5

Canine Blood Analysis: Serum, Hematological, and Biochemical Profiles

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Blood samples obtained by jugular or cephalic venipuncture from each dog using the vacutainer blood collection system were drawn into 2 different types of tubes: with no additive and containing tripotassium ethylenediaminetetraacetic acid (K3EDTA). After collection, samples without additive were centrifuged (ALC 4235 A, Milan, Italy) at 3000 rpm for 20 min. Serum samples obtained after centrifugation were divided into aliquots and processed. Hematological evaluations were performed using a hematology analyzer on the basis of focused flow impedance and flow cytometry (ProCyte Dx, Idexx Laboratories, Westbrook, ME, USA). Serum obtained from centrifugation was used to perform a biochemical examination using a chemistry analyzer (Catalyst Dx Analyzer, Idexx Laboratories, Westbrook, ME, USA). Amino-transferase (ALT), alkaline phosphatase (ALP), glucose (GLU), urea (URE), total protein (TP), albumin (ALB), creatinine (CREA), sodium (Na+), potassium (K+), and total Ca2+ were assayed.
Pugliese M., La Maestra R., Passantino A., Cristarella S., De Majo M., Biondi V, & Quartuccio M. (2020). Electrocardiographic Findings in Bitches Affected by Closed Cervix Pyometra. Veterinary Sciences, 7(4), 183.
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6

Complete Blood Count and Lipid Panel

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CBC analysis was performed by the Comparative Pathology Laboratory at the Icahn School of Medicine at Mount Sinai using an IDEXX ProCyte Dx Hematology Analyzer (IDEXX BioResearch). Cell counts of RBCs, WBCs, platelets, monocytes, lymphocytes, and neutrophils were obtained using standard procedures according to the manufacturer’s instructions. Plasma was sent to IDEXX laboratories for chemical testing. Levels of total cholesterol, HDL cholesterol, LDL cholesterol, and triglycerides were measured according to standard procedures using a Catalyst Dx Analyzer (IDEXX BioResearch).
Lecce L., Xu Y., V’Gangula B., Chandel N., Pothula V., Caudrillier A., Santini M.P., d’Escamard V., Ceholski D.K., Gorski P.A., Ma L., Koplev S., Bjørklund M.M., Björkegren J.L., Boehm M., Bentzon J.F., Fuster V., Kim H.W., Weintraub N.L., Baker A.H., Bernstein E, & Kovacic J.C. (2021). Histone deacetylase 9 promotes endothelial-mesenchymal transition and an unfavorable atherosclerotic plaque phenotype. The Journal of Clinical Investigation, 131(15), e131178.
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7

Equine Biochemistry Profiling Using Idexx Catalyst

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An IDEXX Catalyst Dx Analyzer (Idexx Catalyst Chemistry Analyzer, Westbrook, ME) was used for biochemical profiles. The Equine 15 Clip (eIdexx Equine Clip 15, Westbrook, ME) was used for comprehensive biochemistry testing and included albumin, globulin, total protein, gamma‐glutamyl transferase (GGT), creatinine, blood urea nitrogen (BUN), BUN/creatinine ratio, calcium, aspartate aminotransferase (AST), alkaline phosphatase (ALKP) total bilirubin, and creatine kinase (CK). Each horse had biochemistry profiles run on pregabapentin plasma and on days 7 and 14 for each dose of 40 or 120 mg/kg.
Gold J.R., Grubb T.L., Cox S., Malavasi L, & Villarino N.L. (2022). Pharmacokinetics and pharmacodynamics of repeat dosing of gabapentin in adult horses. Journal of Veterinary Internal Medicine, 36(2), 792-797.
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8

Serum Biomarkers in Mouse Model

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Serum from mice was collected and frozen at −80°C. Serum CK and LDH concentrations were analyzed using the Catalyst DX analyzer (IDEXX) following the manufacturer’s instructions. The cTnI content was determined using the Mouse cTnI ELISA kit (H149-2; Jiancheng Biotech) by a microplate reader.
Wang T.X., Duan K.L., Huang Z.X., Xue Z.A., Liang J.Y., Dang Y., Zhang A., Xiong Y., Ding C., Guan K.L, & Yuan H.X. (2022). Tanshinone functions as a coenzyme that confers gain of function of NQO1 to suppress ferroptosis. Life Science Alliance, 6(1), e202201667.
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