Tg concentrations were measured using the Immulite 2000 xpi Immunoassay System analyser (Siemens Heatlhcare Diagnostics, United Kingdom). The method has an analytical sensitivity of 0.2 ng/ml and a functional sensitivity of 0.9 ng/ml.
Basal serum samples taken from each patient were screened for the presence of Tg antibodies using the Immulite 2000 xpi Immunoassay System analyser, with an analytical sensitivity of 2.2 IU/ml. Neck ultrasonography was performed using a Siemens Versa pro and a Hitachi EUB-6500 (both featuring a colour Doppler function), with a high frequency linear probe (7.5 MHz). WBS was performed with a Symbia T2 gamma camera (Siemens) using a high energy collimator with a scanning speed of 10 cm/min. Diagnostic WBS was performed 72 hours after the administration of 180 MBq 131I (rhTSH) or 80 MBq 131I (TWD). Post-therapy WBS was performed on Day 5 after radioactive iodine treatment.
Basal serum samples taken from each patient were screened for the presence of Tg antibodies using the Immulite 2000 xpi Immunoassay System analyser, with an analytical sensitivity of 2.2 IU/ml. Neck ultrasonography was performed using a Siemens Versa pro and a Hitachi EUB-6500 (both featuring a colour Doppler function), with a high frequency linear probe (7.5 MHz). WBS was performed with a Symbia T2 gamma camera (Siemens) using a high energy collimator with a scanning speed of 10 cm/min. Diagnostic WBS was performed 72 hours after the administration of 180 MBq 131I (rhTSH) or 80 MBq 131I (TWD). Post-therapy WBS was performed on Day 5 after radioactive iodine treatment.