Signa hdx 3t

Manufactured by GE Healthcare

Sourced in United States

The Signa HDx 3T is a high-field magnetic resonance imaging (MRI) system developed by GE Healthcare. It operates at a magnetic field strength of 3 Tesla, providing high-resolution images for detailed diagnostic analysis. The system is designed to deliver reliable and consistent performance in clinical settings.

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Lab products found in correlation

Signa advantage, by GE Healthcare (1 mentions) Signa hdxt 3t, by GE Healthcare (1 mentions) Signa hdxt 1.5t, by GE Healthcare (1 mentions) Signa hdx 1.5t, by GE Healthcare (1 mentions) Signa excite 1.5t, by GE Healthcare (1 mentions) Magnetom verio, by Siemens (1 mentions) Magnevist, by Bayer (1 mentions) Magnetom trio, by Siemens (1 mentions) Magnetom aera, by Siemens (1 mentions) Achieva 3t x, by Philips (1 mentions) Signa infinity twinspeed with excite, by GE Healthcare (1 mentions) Magnetom verio 3t, by Siemens (1 mentions)

Close spelling variants of this product

Signa HDx 3T scanner GE 3T Signa® HDx MR scanner 3T Signa® HDx MR scanner Signa HDx 3T system SIGNA HDx 3T MRI system GE Signa HDx 3T 3T Signa HDx MRI scanner Signa HDx Signa 3T

8 protocols using signa hdx 3t

Liver Lesion MRI Evaluation Protocol

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A total of 91 patients with liver space-occupying lesions (145 lesions), were inspected by MRI (Signa 3T HDx; GE Healthcare, Chicago, IL, USA) at Zhongnan Hospital of Wuhan University (Wuhan, China) from November 2015 and May 2016. Lesions were collected from all patients, including 60 males and 31 females, between 26–82 years of age, with an average age of 53 years old. Patients were divided into two groups, according to the presence of benign or malignant lesions. The malignant lesion group (M) consisted of 36 patients (26 males and 10 females), including 22 cases (18 males and 4 females) of liver cancer, and 14 cases (8 males and 6 females) of liver metastatic tumor; the benign lesion group (B) consisted of 55 patients (34 males and 21 females), including 36 cases (21 males and 9 females) of liver hemangioma, 11 cases (6 males and 5 females) of liver cyst, 5 cases (4 males and 1 female) of focal nodular hyperplasia, and 3 cases (3 males) of liver abscess. The present study was conducted in accordance with the declaration of Helsinki. Ethical approval was gained from the Ethics Committee of Wuhan University (Wuhan, China), and written informed consent was obtained from all study participants.

Li R., Wu G, & Wang R. (2017). Application values of 3.0T magnetic resonance diffusion weighted imaging for distinguishing liver malignant tumors and benign lesions. Oncology Letters, 15(2), 2091-2096.

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Cardiac MRI Evaluation of Cell Injection

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Cardiac MRI (Signa 3 T HDx, General Electric Medical Systems, WI, USA) was performed using a dedicated mouse coil (Rapid MR International, Germany). Mice were imaged at days 1, 7, and 14 after cell injection. Mice were anesthetized with 1-2% isoflurane at 2 L/min oxygen and placed in the supine position. Electrocardiographic gating was obtained with two subcutaneous precordial leads and body temperature was monitored with a rectal probe throughout the scan (SA Instruments, Inc, NY, USA). Left ventricular function was evaluated with electrocardiographically triggered fast spoiled gradient-recalled echo (FSPGR) sequence (TR 24 ms, TE 10 ms, FA 45, field of view (FOV) 6 cm², matrix 256 × 256, slice gap 0 mm, slice thickness 1 mm, NEX 4, 2 excitations, and 20 cardiac phases). In order to define the relationship of signal intensity differences between the Molday ION and MEs regions, scaled to image noise, we measured the signals from Molday ION and MEs region (using OsiriX software) and divided them to the noise signal. It is noteworthy that the measurements were performed 5 times and the regions of interest’s size remained constant.

Mahmoudi M., Tachibana A., Goldstone A.B., Woo Y.J., Chakraborty P., Lee K.R., Foote C.S., Piecewicz S., Barrozo J.C., Wakeel A., Rice B.W., Bell III C.B, & Yang P.C. (2016). Novel MRI Contrast Agent from Magnetotactic Bacteria Enables In Vivo Tracking of iPSC-derived Cardiomyocytes. Scientific Reports, 6, 26960.

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MRI Imaging for PET Co-registration

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As previously described (Parsey et al., 2000 (link)), MRI images were acquired on either a 1.5T Signa Advantage or a 3T Signa HDx system (General Electric Medical Systems, Milwaukee, WI) for co-registration with PET images and extraction of ROIs.

Gopaldas M., Zanderigo F., Zhan S., Ogden R.T., Miller J.M., Rubin-Falcone H., Cooper T.B., Oquendo M.A., Sullivan G., Mann J.J, & Sublette M.E. (2019). Brain Serotonin Transporter Binding, Plasma Arachidonic Acid and Depression Severity: a Positron Emission Tomography Study of Major Depression. Journal of affective disorders, 257, 495-503.

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Resting-State fMRI in Intractable Epilepsy

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Data were collected from 10 consecutive patients (ages 20-58 years, 35.3±15.9 years, 5 males) with intractable epilepsy who underwent presurgical evaluation at Mayo Clinic (Rochester, MN). Clinical information was listed in Table 1. Resting state functional images were acquired using a General Electric 3T Signa HDx (Waukesha, Wisconsin) scanner. Each set of data was 20 min using a T2*-weighted EPI sequence. TR=3000 ms, flip angle =90, 3 mm isotropic voxel, 30±2 slices. A spoiled gradient recalled T₁ weighted anatomical image before and after operation was acquired for coregistration with functional data (1 mm isotropic voxel, 120 or 190 slices). The study was conducted according to a protocol approved by the Institutional Review Boards (IRB) of Mayo Clinic and the University of Minnesota respectively.

Zhang C.H., Lu Y., Brinkmann B., Welker K., Worrell G, & He B. (2014). Lateralization and Localization of Epilepsy Related Hemodynamic Foci Using Presurgical fMRI. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 126(1), 27-38.

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Contrast-Enhanced MRI for Tumor Ablation Monitoring

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All pre-procedure MRI exams were performed within 30 days (mean 11.5 days, range 1–27 days) before the procedure using one of the following 1.5T or 3T MRI scanners with a phased-array body coil: MAGNETOM Aera, MAGNE-TOM Trio, or MAGNETOM Verio (Siemens AG, Munich, Germany); or Signa EXCITE 1.5T, Signa HDx 1.5T, Signa HDx 3T, Signa HDxt 1.5T, or Signa HDxt 3T (GE Healthcare, Waukshesha, WI). CE-MR images were acquired using a T1-weighted 3D gradient-echo sequence before and 30, 60, and 90 seconds after intravenous administration of 0.1 mmol/kg of gadopentetate dimeglumine (Magnevist, Bayer HealthCare Pharmaceuticals, Berlin, Germany). The post-procedure MR images were also acquired in the same manner, within 72 hours following the procedure. The patients were followed up with CE-MR or CT images at regular intervals, at least for a year. We defined local recurrence as a post-procedural development of tumor adjacent to or within ablation area [33 (link),32 (link)]. Among the 21 patients, recurrences were found in five patients.

Tani S., Tatli S., Hata N., Garcia-Rojas X., Olubiyi O.I., Silverman S.G, & Tokuda J. (2016). Three-dimensional quantitative assessment of ablation margins based on registration of pre- and post-procedural MRI and distance map. International journal of computer assisted radiology and surgery, 11(6), 1133-1142.

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Resting-State fMRI Motion Analysis Protocol

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All participants received a structural MR imaging exam on a GE Signa HDx 3T system using an 8 channel head coil (TR = 7.5 ms, TE = 3 ms, slice thickness= 1 mm, matrix = 256 × 256, FOV = 240 mm). Resting state fMRI was 5 minutes in duration. 150 echo-planner imaging (EPI) volumes were acquired with the following parameters: TR = 2000 ms, TE = 30 ms, matrix = 64*64, FOV = 240 mm, slice thickness = 3 mm, 40 continuous axial oblique slices (one voxel = 3.75×3.75×3 mm). During the resting state exam all subjects were instructed to keep their eyes closed, not to sleep, and to “not think of anything in particular.” We investigated the potential effects of motion on functional connectivity given recent concerns in the literature (e.g. Power et al 2012 (link)) by examining both relative and absolute motion displacement during the resting state fMRI exam.

Gruner P., Vo A., Argyelan M., Ikuta T., Degnan A.J., John M., Peters B.D., Malhotra A.K., Uluğ A.M, & Szeszko P.R. (2014). Independent component analysis of resting state activity in pediatric obsessive‐compulsive disorder. Human Brain Mapping, 35(10), 5306-5315.

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Brain MRI in Severely Delirious ICU Patients

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Brain MRI was performed in patients with the most severe and persistent delirium (> 3 days during ICU stay) and/or abnormal neurological examination. Brain MRI was only feasible if patients were hemodynamically stable (i.e., patients without catecholamines) and non-hypoxemic (FiO₂ < 40% and PEEP < 8 or < 4 L/min oxygen) and without contra-indication to MRI. Patients underwent a gadolinium-enhanced brain MRI on a 3T MRI scanner (Achieva 3Tx, Philips, Best, The Netherlands, or SIGNA HDX 3T, GE, Milwaukee, USA). Acquisition parameters are summarized in Additional file 1.

Helms J., Kremer S., Merdji H., Schenck M., Severac F., Clere-Jehl R., Studer A., Radosavljevic M., Kummerlen C., Monnier A., Boulay C., Fafi-Kremer S., Castelain V., Ohana M., Anheim M., Schneider F, & Meziani F. (2020). Delirium and encephalopathy in severe COVID-19: a cohort analysis of ICU patients. Critical Care, 24, 491.

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Multimodal MRI Imaging of Brain Aneurysms

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1.5T MR scanner (Signa Infinity Twin speed with Excite, GE Healthcare) with 8-channel neurovascular array coil and two 3T MR scanners (Signa HDx 3T, GE Healthcare and MAGNETOM Verio 3T, Siemens Healthcare) with 8- and 12-channel neurovascular array coils were utilized in image acquisition. Three ruptured and six unruptured aneurysms included in the study had been imaged using 1.5T MR scanner whereas 6 ruptured and 22 unruptured aneurysms had been imaged using 3T MR scanner with 8-channel neurovascular array coil. The other 3T MR scanner with 12-channel neurovascular array coil had been utilized in the image acquisition of one ruptured and 10 unruptured aneurysms in the study. The imaging parameters of 3D TOF MRA and 3D cine PC MRI are shown in Table 1.

Perera R., Isoda H., Ishiguro K., Mizuno T., Takehara Y., Terada M., Tanoi C., Naito T., Sakahara H., Hiramatsu H., Namba H., Izumi T., Wakabayashi T., Kosugi T., Onishi Y., Alley M., Komori Y., Ikeda M, & Naganawa S. (2020). Assessing the Risk of Intracranial Aneurysm Rupture Using Morphological and Hemodynamic Biomarkers Evaluated from Magnetic Resonance Fluid Dynamics and Computational Fluid Dynamics. Magnetic Resonance in Medical Sciences, 19(4), 333-344.

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