Echomri 3 in 1 system nuclear magnetic resonance spectrometer

Manufactured by Echo Medical Systems

Sourced in United States

The EchoMRI 3-in-1 system is a nuclear magnetic resonance spectrometer designed for laboratory use. It provides analysis and measurement capabilities through the application of nuclear magnetic resonance principles.

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Lab products found in correlation

Oxymax lab animal monitoring system, by Columbus Instruments (1 mentions) Comprehensive lab animal monitoring system, by Columbus Instruments (1 mentions)

Close spelling variants of this product

EchoMRI 3-in-1 system nuclear magnetic EchoMRI-3-in-1 system EchoMRI 3-in-1 EchoMRI 3-1 The 3-in-1 EchoMRI system EchoMRI

4 protocols using echomri 3 in 1 system nuclear magnetic resonance spectrometer

Metabolic Profiling of Mice

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Bodyweight and body composition were measured in ad-lib fed conscious mice using an EchoMRI^™ 3-in-1 system nuclear magnetic resonance spectrometer (Echo Medical Systems, Houston, TX) to determine whole-body lean and fat mass. Mice were individually placed in the Oxymax Lab Animal Monitoring System (Columbus Instruments) with free access to food and water. After overnight acclimation, oxygen consumption, the amount of carbon dioxide produced, food and liquid intake, and locomotor activity (beam breaks) were determined. Respiratory exchange ratios were calculated by dividing the volume of carbon dioxide produced by the volume of oxygen consumed (VCO₂/VO₂).

Kumar A., Sundaram K., Mu J., Dryden G.W., Sriwastva M.K., Lei C., Zhang L., Qiu X., Xu F., Yan J., Zhang X., Park J.W., Merchant M.L., Bohler H.C., Wang B., Zhang S., Qin C., Xu Z., Han X., McClain C.J., Teng Y, & Zhang H.G. (2021). High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance. Nature Communications, 12, 213.

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Noninvasive Body Composition Analysis

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Body weight and body composition were measured in ad-lib fed conscious mice using EchoMRI 3-in-1 system nuclear magnetic resonance spectrometer (Echo Medical Systems) to determine whole-body lean and fat mass.

Qiu J., Yue F., Zhu P., Chen J., Xu F., Zhang L., Kim K.H., Snyder M.M., Luo N., Xu H.W., Huang F., Tao W.A, & Kuang S. (2023). FAM210A is essential for cold-induced mitochondrial remodeling in brown adipocytes. Nature Communications, 14, 6344.

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Assessing Body Composition and Cardiovascular Parameters in Mice

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At 39 weeks (ie, end of life), body weight and body composition were measured in ad-lib fed conscious mice using EchoMRI 3-in-1 system nuclear magnetic resonance spectrometer (Echo Medical Systems, Houston, TX, USA) to determine whole body lean and fat mass. Subsequently, systolic and diastolic blood pressure and heart rate were measured by noninvasive tail-cuff volume pressure recording (VPR) using the CODA 8 BP System (Kent Scientific Corporation, Torrington, CT, USA). Briefly, mice were placed into an animal holder on a warming platform and tails were threaded into an O-cuff and then a VPR cuff. Before initiating the blood pressure measurement, a noncontact infrared thermometer was used to confirm that the temperature at the base of the tail was 32-35°C. Subsequently, two runs of 30 measurement cycles were performed to obtain measurement averages. All assays were performed by an expert technician blinded to the experimental group of each mouse.

Narapareddy L., Rhon-Calderon E.A., Vrooman L.A., Baeza J., Nguyen D.K., Mesaros C., Lan Y., Garcia B.A., Schultz R.M, & Bartolomei M.S. (2021). Sex-specific effects of in vitro fertilization on adult metabolic outcomes and hepatic transcriptome and proteome in mouse. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 35(4), e21523.

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Comprehensive Metabolic Phenotyping in Mice

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Body weight and body composition were measured in ad-lib fed
conscious mice using EchoMRI™ 3-in-1 system nuclear magnetic
resonance spectrometer (Echo Medical Systems, Houston, TX) to determine
whole body lean and fat mass. Indirect calorimetry was performed in
individually housed mice using a 20-channel open-circuit indirect
calorimeter, in which 10 cages were mounted inside two thermally controlled
cabinets, maintained at 22°C (Comprehensive Lab Animal Monitoring
System; Columbus Instruments, Columbus, OH, USA). After overnight
acclimation (20 hours), oxygen consumption (VO2), the amount of carbon
dioxide produced (VCO2), energy expenditure, food and water intake,
ambulatory and locomotor activity (infrared beam breaks) were determined
during an initial period of fasting (9am-5pm), as well as for the following
40 hours wherein mice were fed ad libitum. Average
respiratory exchange ratio (RER) was calculated as the ratio of VCO2:VO2
over 48 hours. Energy expenditure was calculated as heat (kcal/hr)=(3.815
+1.232 × RER) × VO2). The metabolic studies were performed at
the Penn Diabetes Research Center Rodent Metabolic Phenotyping Core
(University of Pennsylvania).

Hui S., Cowan A.J., Zeng X., Yang L., TeSlaa T., Li X., Bartman C., Zhang Z., Jang C., Wang L., Lu W., Rojas J., Baur J.A, & Rabinowitz J.D. (2020). Quantitative fluxomics of circulating metabolites. Cell metabolism, 32(4), 676-688.e4.

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