Sureselect xt v6 human all exon kit

Manufactured by Agilent Technologies

Sourced in United States

The SureSelect XT V6 Human All Exon kit is a targeted sequencing solution designed to capture and enrich all human exonic regions for downstream sequencing analysis. The kit utilizes RNA baits to selectively capture and enrich the coding regions of the human genome, enabling efficient and cost-effective sequencing of the exome.

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Lab products found in correlation

V3 high throughput kit, by Illumina (2 mentions) Nextseq 500 system, by Illumina (2 mentions)

Spelling variants of this product

SureSelect Human All Exon V6 (111 citations) SureSelect XT (106 citations) SureSelect V6 kit (10 citations) SureSelect kits (5 citations)

2 protocols using sureselect xt v6 human all exon kit

Exome Sequencing for Genetic Disorders

Cited 2 times

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Exome sequencing (ES) for families L1096, L692, L1347, and GL 9307100 was performed in the GRC NGS core facility, using the SureSelect XT V6 Human All Exon kit (Agilent Technologies, Santa Clara, CA, USA) following the manufacturer’s protocol. After library quantification and pooling, samples were sequenced on an Illumina NextSeq 500 System (Illumina, San Diego, CA, USA) using the Illumina V3 High Throughput kit.
For probands in families GL10179 and GL9988 library preparation, sequencing and bioinformatics analysis were performed using the OtoSCOPE® V8 platform (152 genes) (Agilent Technologies, Santa Clara, CA, USA) in the Molecular Otolaryngology and Renal Research Laboratories (MORL; University of Iowa, Iowa City, IA, USA), as described (17 (link)–19 (link)).

Mohseni M., Akbari M., Booth K.T., Babanejad M., Azaiez H., Ardalani F., Arzhangi S., Jalalvand K., Nikzat N., Ghodratpour F., jamali P., Adeli O.A., Habibi H., Kahrizi K, & Najmabadi H. (2020). When transcripts matter: delineating between non-syndromic hearing loss DFNB32 and hearing impairment infertile male syndrome (HIIMS). Journal of human genetics, 65(7), 609-617.

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Whole Exome Sequencing for Family

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WES (Whole Exome Sequencing) for the family was performed, using the SureSelect XT V6 Human All Exon kit (Agilent Technologies, Santa Clara, CA, USA) following the manufacturer’s protocol. After library quantification and pooling, samples were sequenced on an Illumina NextSeq 500 System (Illumina, San Diego, CA, USA) using the Illumina V3 High Throughput kit. For 3 people in the family (II.11, II.16, II.18) library preparation, sequencing, and bioinformatics analysis were performed using illumina Platform.

Akbari M., Mohebi M., Berjis K., Ghahremani A., Modarressi M.H, & Ghafouri-Fard S. (2022). A novel variant in TLE6 is associated with embryonic developmental arrest (EDA) in familial female infertility. Scientific Reports, 12, 17664.

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