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Diapact crrt

Manufactured by B. Braun
Sourced in Germany

The Diapact CRRT is a continuous renal replacement therapy (CRRT) device designed for the treatment of acute kidney injury. It provides automated control and monitoring of blood and dialysate/replacement fluid flow rates, temperature, and pressure during CRRT procedures.

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2 protocols using diapact crrt

1

Vascular Access for CRRT and HP

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Using the Seldinger technique, an acute dual lumen catheter was inserted percutaneously either through the femoral vein or the right internal jugular for vascular access. Hemofiltration was carried out using a B. Braun Diapact CRRT machine and used a polyacrylonitrile hemofilter (B. Braun Diacap Acute L, Melsungen Germany). Blood flow rate was 200 to 250 mL/min. Replacement solution was added in pre-dilutionmode. Anticoagulation was obtained with low molecular weight heparin, and activated partial thromboplastin time was adjusted to 60 to 70 s. In combined group, concurrent PHVHF and HP were performed for the first 2 h. The HP cartridge preceded the hemofilter in the circuit. Hemoperfusion was undertaken with a resin cartridge (HA-330, Zhuhai Lizhu Group of Biological Material Co, Ltd. China) once a day. PHVHF was carried out with a daily schedule of HVHF(85 mL/kg/h)for 6 h followed by CVVH (35 mL/kg/h) for 18 h.5 In another group, CVVH (35 mL/kg/h) was performed for 24 h.
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2

Continuous Veno-Venous Hemodiafiltration Procedure

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Continuous veno-venous hemodiafiltration was performed using Diapact CRRT B. Braun Co. (Melsungen, Germany). Synthetic high-volume membrane filters with a surface area of 1.5-2.2 m 2 were used and changed every 24 h or when filter blocking occurred. Vascular access was obtained by a double-or triple-lumen catheter using the femoral or jugular vein. Anticoagulation was provided with non-fractioned heparin, adjusting the dosage according to the value of activated partial thromboplastin time in the plasma. The procedure was performed with a low dose of heparin or without it when possible. The substitution fluid infusion rate was 1,250-1,750 mL/h in a pre-diluted or post-diluted manner, comprising 30-42 L of the total substitute in 24 h. The blood flow rate was 50-200 mL/min. The ultrafiltration rate was adjusted according to the diuresis and fluid balance.
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