Zidovudine, abacavir, lamivudine, efavirenz, nevirapine, ritonavir, and nelfinavir were obtained from Sigma. Emtricitabine, tenofovir disoproxil fumarate, darunavir, dolutegravir and elvitegravir were obtained from MedChem Express. LysoSensor (DN160) was obtained from Fisher Thermo Scientific. Aβ1–40 and Aβ1–42 ELISA kits were obtained from Wako. ML-SA1 was obtained from Tocris Bioscience.
Abacavir
Manufactured by Merck Group
Abacavir is a nucleoside reverse transcriptase inhibitor (NRTI) used in the treatment of HIV infection. It blocks the reverse transcriptase enzyme, which is essential for the replication of the HIV virus.
Automatically generated - may contain errors
Lab products found in correlation
Lamivudine, by Merck Group (3 mentions)
Nelfinavir, by Merck Group (2 mentions)
Ritonavir, by Merck Group (2 mentions)
Zidovudine, by Merck Group (2 mentions)
Nevirapine, by Merck Group (1 mentions)
Darunavir, by MedChemExpress (1 mentions)
Dolutegravir, by MedChemExpress (1 mentions)
Elvitegravir, by MedChemExpress (1 mentions)
Aβ1 40, by Fujifilm (1 mentions)
Aβ1 42 elisa kits, by Fujifilm (1 mentions)
Efavirenz, by Merck Group (1 mentions)
Ml sa1, by Bio-Techne (1 mentions)
Indinavir, by Merck Group (1 mentions)
Atazanavir, by Merck Group (1 mentions)
Saquinavir, by Merck Group (1 mentions)
Amprenavir, by Merck Group (1 mentions)
Lopinavir, by Merck Group (1 mentions)
Tenofovir, by Merck Group (1 mentions)
Stavudine, by Merck Group (1 mentions)
3 protocols using abacavir
1
Evaluating Anti-HIV and Anti-Alzheimer's Compounds
2
Synthesis of HIV Protease Inhibitors
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The synthetic methods of nonpeptidic PIs, GRL-036, -121, and -139 were recently published (Ghosh et al., 2017 (link)), while GRL-142 was newly designed and synthesized. The method of synthesis of GRL-142 will be published elsewhere by A. K. Ghosh et al. DRV was synthesized as previously described (Ghosh et al., 2004 (link)). Saquinavir (SQV), indinavir (IDV), nelfinavir (NFV), ritonavir (RTV), tipranavir (TPV), amprenavir (APV), lopinavir (LPV), atazanavir (ATV), zidovudine (AZT), lamivudine (3TC), and abacavir (ABC) were purchased from Sigma-Aldrich (St. Louis, MO). Tenofovir disoproxil fumarate (TDF) was purchased from BioVision (Milpitas, CA).
3
Parental Fly Drug Exposure Impact
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Parental fly crosses were settled on standard cornmeal added of the below-listed drugs with the reported final concentration: stavudine 10 μM, azidotimidine 10 μM, tenofovir 10 μM, abacavir (#SML0089 Sigma) 10 μM, rilpivirine (#10410 Sigma) 10 μM, enoxacin (#AB143281 Abcam) 10 μM, and lamivudine (#L1295 Sigma) 10 μM. For each drug, a vehicle-only control group was arranged. Parental flies have been maintained 24 h in the tubes to allow the embryo laying. Synchronized embryos were grown to obtain third instar larvae to be tested for mobility or to be analyzed for NMJ morphology.
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