Aztreonam

Manufactured by Bioanalyse

Aztreonam is a synthetic monocyclic beta-lactam antibiotic that is effective against a variety of gram-negative bacteria. It works by inhibiting cell wall synthesis, leading to cell death.

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Lab products found in correlation

2 protocols using aztreonam

Antimicrobial Susceptibility Testing of ESBL-Producing K. pneumoniae

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The ESBL-producing K. pneumoniae isolates were tested for
antimicrobial susceptibility testing (AST) using disk diffusion technique
according to the Clinical and Laboratory Standards Institute (CLSI)
instructions⁹. Antimicrobials were classified as follows: aztreonam (ATM, 30 μg),
gentamicin (CN, 10 μg), ciprofloxacin (CIP, 5 μg), ceftazidime (CAZ, 30 μg),
levofloxacin (LEV, 5 μg), amoxicillin/clavulanate (AMC, 30 μg), trimethoprim
(TMP, 5 μg), norfloxacin (NOR, 10 μg), cefotaxime (CTX, 30 μg), nitrofurantoin
(F, 300 μg), imipenem (IPM, 10 μg), chloramphenicol (C, 30 μg), tetracycline
(TE, 30 μg), and ceftriaxone (CRO, 30 μg) (Bioanalyse, Turkey). MDR isolates
were determined according to the previous definition (resistance to at least one
member of three antibiotics classes)¹⁰. Escherichia coli ATCC 25922 and K.
pneumoniae ATCC 700603 were used as quality control strains.

Raouf F.E., Benyagoub E., Alkhudhairy M.K., Akrami S, & Saki M. (2022). Extended-spectrum beta-lactamases among Klebsiella pneumoniae from Iraqi patients with community-acquired pneumonia. Revista da Associação Médica Brasileira, 68(6), 833-837.

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Antimicrobial Susceptibility Testing: Disk Diffusion

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Antimicrobial susceptibility of the isolates was performed by the disk diffusion method according to the instructions of CLSI [30 ] using Mueller-Hinton agar (HIMEDIA, India). The used antimicrobials were obtained from Bioanalyse/ Turkey and included: ampicillin (AMP: 10 μg); amoxicillin-clavulanic acid (AMC: 20/10 μg); cefoxitin (FOX: 30 μg); cefotaxime (CTX: 30 μg); ceftazidime (CAZ: 30 μg); ceftriaxone (CRO: 30 μg); cefepime (FEP: 30 μg); aztreonam (ATM: 30 μg); imipenem (IPM: 10 μg); meropenem (MEM: 10 μg); gentamicin (CN: 10 μg); amikacin (AK: 30 μg); tetracycline (TE: 30 μg); nalidixic acid (NA: 30 μg); ciprofloxacin (CIP: 5 μg); trimethoprim-sulfamethoxazole (SXT: 1.25/23.75 μg); and nitrofurantoin (F: 300 μg).

Gatya Al-Mayahie S.M., Al-Guranie D.R., Hussein A.A, & Bachai Z.A. (2022). Prevalence of common carbapenemase genes and multidrug resistance among uropathogenic Escherichia coli phylogroup B2 isolates from outpatients in Wasit Province/ Iraq. PLoS ONE, 17(1), e0262984.

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