737 analyzer

Participants underwent a gallbladder ultrasound in NHANES III program. A hepatic steatosis examination was conducted to assess the presence of fat within the hepatic parenchyma. The archived original gallbladder ultrasonography videotapes and NHANES III results observed during the MEC examination were reviewed.
Hepatic steatosis was evaluated using the following five criteria: parenchymal brightness, liver to kidney contrast, deep beam attenuation, bright vessel walls, and gallbladder wall definition. The presence, absence, or degree of these five criteria was recorded. An experienced radiologist supervised the trained ultrasound image readers. Aside from normal sonography patterns, the degree of hepatic steatosis severity was classified as mild, moderate, or severe.
Diabetes was defined as a fasting plasma glucose level ≥126 mg/dL, glycated hemoglobin level ≥6.5%, diabetes history, or hypoglycemia medication use. A trained research assistant measured blood pressure. Waist circumference was measured by a steel measuring tape at the iliac crest from the right side of the body. Serum HDL cholesterol, triglycerides, and glycated hemoglobin were measured via chemical analyses (Hitachi 737 Analyzer; Indianapolis, Indiana)

Hepatic steatosis was recorded by ultrasound (Toshiba Sonolayer SSA-90A) and evaluated using the following five parameters (liver to kidney contrast, parenchymal brightness, bright vessel walls, deep beam attenuation, and gallbladder wall definition) by three trained ultrasound readers. The degree of hepatic steatosis was graded as normal, mild, moderate, or severe.
MAFLD was defined as the presence of hepatic steatosis (mild to severe) with one or more of the following: (i) overweight or obese (body mass index ≥ 25 kg/m²); (ii) type 2 diabetes (fasting plasma glucose ≥ 126 mg/dL or HbA1c ≥ 6.5% or the use of anti-hyperglycemic agents); or (iii) at least 2 metabolic abnormalities described by any two indicators: (a) waist circumference (WC) ≥ 102 cm in men or ≥ 88 cm in women; (b) blood pressure ≥ 130/85 mmHg or taking anti-hypertension drugs; (c) raised triglycerides (≥ 1.70 mmol/L); (d) reduced HDL cholesterol (plasma HDL < 1.0 mmol/L for men and < 1.3 mmol/L for women); (e) prediabetes status (FPG 5.6–6.9 mmol/L, or 2-h post-load glucose levels 7.8–11.0 mmol or HbA1c 5.7–6.4%); (f) HOMA-IR ≥ 2.5; (g) plasma C-reactive protein (CRP) level > 2 mg/L [3 (link)].
Blood samples for SUA measurement were measured by uricase-mediated oxidation to form allantoin and hydrogen peroxide (Hitachi 737 Analyzer), and data were rounded 1 decimal places (0.1 mg/dL) [22 ].