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Calmidazolium chloride

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Calmidazolium chloride is a calmodulin antagonist that inhibits calmodulin-dependent processes. It is a white crystalline powder soluble in water and organic solvents.

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Lab products found in correlation

Lopac1280 library, by Merck Group (2 mentions) Etoposide, by Merck Group (2 mentions) 4 hydroxytamoxifen, by Merck Group (2 mentions) Rottlerin, by Merck Group (2 mentions) Chir99021, by Selleck Chemicals (2 mentions) Strophanthidin, by Merck Group (2 mentions) Rotenone, by Merck Group (2 mentions) Digoxin, by Merck Group (2 mentions) Bufalin, by Merck Group (2 mentions) Diphenyleneiodonium chloride, by Merck Group (2 mentions) Alisertib, by Selleck Chemicals (2 mentions) Jnk in 8, by Selleck Chemicals (2 mentions) Barasertib, by Selleck Chemicals (2 mentions) Doxorubicin hydrochloride, by Cayman Chemical (2 mentions) Ouabain octahydrate, by Merck Group (2 mentions) Q vd oph hydrate, by Merck Group (2 mentions) Bix01294, by Selleck Chemicals (2 mentions) Tozasertib, by Selleck Chemicals (2 mentions) Jfd00244, by Merck Group (2 mentions) Cgp 74514a hydrochloride, by Merck Group (2 mentions)

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Calmidazolium (4 citations)

3 protocols using calmidazolium chloride

1

Screening Anti-Cancer Stem Cell Agents

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We cultured HCT116, HT29, and DLD-1 cells under standard culture conditions in RPMI-1640 media (Welgene) containing 10% FBS (Atlas Biologicals) and 1 × penicillin-streptomycin (Corning). For the drug treatments, we dissolved JIB-04 (Cayman) and salinomycin (Cayman) in DMSO and diluted the solutions to the appropriate concentrations for the experiments. The following chemicals were used for the primary screening of anti-CSC agents: IOX1 (Cayman), SAHA (Cayman), trichostatin (TSA) (Cayman), EPZ5676 (APEXBIO), eosin Y disodium trihydrate(AMI-5) (Santa Cruz), 2-PCPA(Cayman), sirtinol (Cayman), pargyline (Sigma-Aldrich), paclitaxel (Cayman) 5-FU (Cayman), etoposide (Cayman), nocodazole (Sigma-Aldrich), calmidazolium chloride (Tocris Bioscience), beta-lapachone (Cayman).
Kim M.S., Cho H.I., Yoon H.J., Ahn Y.H., Park E.J., Jin Y.H, & Jang Y.K. (2018). JIB-04, A Small Molecule Histone Demethylase Inhibitor, Selectively Targets Colorectal Cancer Stem Cells by Inhibiting the Wnt/β-Catenin Signaling Pathway. Scientific Reports, 8, 6611.
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2

High-Throughput Compound Screening for Cytotoxicity

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The LOPAC 1,280 library was acquired from Sigma-Aldrich (LO1280). The following compounds were used in this study: ABT-263 (Selleckchem, S1001), Ouabain octahydrate (Sigma-Aldrich, O3125), Diphenyleneiodonium chloride (Sigma-Aldrich, D2926), JFD00244 (Sigma-Aldrich, J4829), CGP-74514A hydrochloride (Sigma-Aldrich, C3353), Etoposide (Sigma-Aldrich, E1383), Palbociclib HCl (Selleckchem, S1116), Digoxin (Sigma-Aldrich, D6003), Digitoxin (MedChemExpress HY-B1357), Bufalin (Sigma-Aldrich, B0261), Q-VD-OPh hydrate (Sigma-Aldrich, SML0063), KCl (BioVision, 2115-100), Doxycycline hydrate (Sigma-Aldrich, D9891), 4-Hydroxytamoxifen (Sigma-Aldrich, H7904), CHIR-99021 (Selleckchem, S2924), JNK-IN-8 (Selleckchem, S4901), BMS-582949 (Selleckchem, S8124), ABT-737 (Selleckchem, S1002), Alisertib (Selleckchem, S1133), Barasertib (Selleckchem, S1147), Tozasertib (Selleckchem, S1048), Doxorubicin hydrochloride (Cayman chemical, 15007), Rotenone (Sigma-Aldrich, R8875), Rottlerin (Sigma-Aldrich, R5648), Calmidazolium chloride (Tocris, 2561), BIX-01294 (Selleckchem, S8006), Mibefadril (Sigma-Aldrich, M5441), Ouabagenin (Santa Cruz, sc-295983), Strophanthidin (Sigma-Aldrich, S6626), Strophanthin K (Sigma-Aldrich, S355445), Liproxstatin-1 (Selleckchem S7699), Necrostatin-1 (Selleckchem S8037), Belnacasan (VX-765; Selleckchem S2228), Curcumin (Sigma-Aldrich, 08511), Sorafenib (Selleckchem S7397).
Guerrero A., Herranz N., Sun B., Wagner V., Gallage S., Guiho R., Wolter K., Pombo J., Irvine E.E., Innes A.J., Birch J., Glegola J., Manshaei S., Heide D., Dharmalingam G., Harbig J., Olona A., Behmoaras J., Dauch D., Uren A.G., Zender L., Vernia S., Martínez-Barbera J.P., Heikenwalder M., Withers D.J, & Gil J. (2019). Cardiac glycosides are broad-spectrum senolytics. Nature metabolism, 1(11), 1074-1088.
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3

High-Throughput Compound Screening for Cytotoxicity

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The LOPAC 1,280 library was acquired from Sigma-Aldrich (LO1280). The following compounds were used in this study: ABT-263 (Selleckchem, S1001), Ouabain octahydrate (Sigma-Aldrich, O3125), Diphenyleneiodonium chloride (Sigma-Aldrich, D2926), JFD00244 (Sigma-Aldrich, J4829), CGP-74514A hydrochloride (Sigma-Aldrich, C3353), Etoposide (Sigma-Aldrich, E1383), Palbociclib HCl (Selleckchem, S1116), Digoxin (Sigma-Aldrich, D6003), Digitoxin (MedChemExpress HY-B1357), Bufalin (Sigma-Aldrich, B0261), Q-VD-OPh hydrate (Sigma-Aldrich, SML0063), KCl (BioVision, 2115-100), Doxycycline hydrate (Sigma-Aldrich, D9891), 4-Hydroxytamoxifen (Sigma-Aldrich, H7904), CHIR-99021 (Selleckchem, S2924), JNK-IN-8 (Selleckchem, S4901), BMS-582949 (Selleckchem, S8124), ABT-737 (Selleckchem, S1002), Alisertib (Selleckchem, S1133), Barasertib (Selleckchem, S1147), Tozasertib (Selleckchem, S1048), Doxorubicin hydrochloride (Cayman chemical, 15007), Rotenone (Sigma-Aldrich, R8875), Rottlerin (Sigma-Aldrich, R5648), Calmidazolium chloride (Tocris, 2561), BIX-01294 (Selleckchem, S8006), Mibefadril (Sigma-Aldrich, M5441), Ouabagenin (Santa Cruz, sc-295983), Strophanthidin (Sigma-Aldrich, S6626), Strophanthin K (Sigma-Aldrich, S355445), Liproxstatin-1 (Selleckchem S7699), Necrostatin-1 (Selleckchem S8037), Belnacasan (VX-765; Selleckchem S2228), Curcumin (Sigma-Aldrich, 08511), Sorafenib (Selleckchem S7397).
Guerrero A., Herranz N., Sun B., Wagner V., Gallage S., Guiho R., Wolter K., Pombo J., Irvine E.E., Innes A.J., Birch J., Glegola J., Manshaei S., Heide D., Dharmalingam G., Harbig J., Olona A., Behmoaras J., Dauch D., Uren A.G., Zender L., Vernia S., Martínez-Barbera J.P., Heikenwalder M., Withers D.J, & Gil J. (2019). Cardiac glycosides are broad-spectrum senolytics. Nature metabolism, 1(11), 1074-1088.
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