Cg tg k18 ace2 2prlmn j mice
The Cg-Tg(K18-ACE2)2Prlmn/J mice are a transgenic mouse model that expresses the human angiotensin-converting enzyme 2 (hACE2) gene under the control of the keratin 18 (K18) promoter. The hACE2 gene is a known receptor for the SARS-CoV-2 virus, which causes COVID-19 in humans. These mice can be used to study the pathogenesis of SARS-CoV-2 infection and evaluate potential therapeutic interventions.
Lab products found in correlation
2 protocols using cg tg k18 ace2 2prlmn j mice
SARS-CoV-2 Infection Dynamics in K18-ACE2 Mice
SARS-CoV-2 Infection in K18-hACE2 Mice
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