As previous studies revealed, CTP scans were performed with the 64-slice detector CT scanner (Philips, Best, the Netherlands) and followed with injection of diluted nonionic contrast material. CTP data were then transferred to a postprocessing workstation (Extended Brilliance Workstation v 3.0, Philips Medical Systems) [22 (link)]. Cerebral blood volume (CBV), cerebral blood flow (CBF), mean transit time (MTT), and time to peak (TTP) were calculated using a deconvolution operation (Extend Brilliance Workstation v 3.0, Philips Medical Systems, USA). Absolute values of CTP parameters are subject to the area of regions of interest (ROIs) and are influenced by physiologic factors such as blood pressure [23 (link), 24 (link)]. Hence, we used the ratio of the values measured in the ipsilateral hemisphere to those in the contralateral hemisphere for CBV, CBF, MTT, and TTP (rCBV, rCBF, rMTT, and rTTP). Four absolute values obtained from 4 consecutive layers of a given territory were averaged to obtain the mean of CBV, CBF, MTT, and TTP in both ipsilateral and contralateral side. ROIs in both hemispheres including frontal lobe, occipital lobe, temporal lobe, and basal ganglia were manually outlined according to the maps of Damasio [25 (link)].
Extended brilliance workstation v 3
Manufactured by Philips
The Extended Brilliance Workstation v 3.0 is a laboratory equipment product from Philips. It is designed to provide a comprehensive platform for data analysis and visualization. The workstation features a high-performance computing system, advanced software tools, and a customizable user interface. The core function of the product is to enable efficient data processing, analysis, and presentation for research and scientific applications.
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Lab products found in correlation
2 protocols using extended brilliance workstation v 3
1
Cerebral Perfusion Analysis via CTP
2
Multiparametric CT Perfusion Protocol
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Multiparametric CT protocol involved a non-enhanced CT, single phase CT angiography and CT perfusion. All CT imaging was performed with 256-slices CT scanner (Brilliance iCT; Philips Medical Systems, Best, Netherlands). CTP acquisition protocol involved injections of intravenous contrast medium and a total scanning time of 60 s. The exposure parameters used were 80 kVp and 150-200 mA s and we performed a three-dimensional axial acquisition on the whole brain volume with a reconstruction of the slices set to 5 mm. CT image processing and analysis were carried out using brain perfusion software (Extended Brilliance Workstation v 3.0, Philips Medical Systems) and Matlab (MathWorks Inc., Natick, MA) with a dedicated code created for this study. Perfusion maps mean transit time (MTT), cerebral blood volume (CBV), and cerebral blood flow (CBF) were obtained from source images using a deconvolution algorithm. Circular ROI was placed in the anatomical area compatible with clinical presentation, while control ROI was automatically positioned symmetrically on the contralateral side. Differences between MTT, CBV, and CBF CT perfusion parameters between ROI placed in the anatomical area compatible with clinical presentation and contralateral ROI were estimated in terms of asymmetry index (AI%), which was calculated for each CTP parameter as follows:
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