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H gly pro arg pro oh gprp

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H-Gly-Pro-Arg-Pro-OH (GPRP) is a peptide compound used in laboratory research. It is a tetrapeptide composed of the amino acids glycine, proline, arginine, and proline. The core function of GPRP is to serve as a biochemical tool for various experimental applications, but a detailed description of its intended use cannot be provided while maintaining an unbiased and factual approach.

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Lab products found in correlation

Anti human cd61 antibody, by BD (2 mentions) Alexa fluor 647 conjugated human fibrinogen, by Thermo Fisher Scientific (2 mentions) Phe pro arg chloromethylketone ppack, by Prolytix (2 mentions) Sigmacote, by Merck Group (2 mentions) Dade innovin prothrombin time reagent, by Siemens (1 mentions) Dasatinib, by Selleck Chemicals (1 mentions) Gr144053, by Bio-Techne (1 mentions) Alexa fluor 488 conjugated annexin 5, by Thermo Fisher Scientific (1 mentions) Corn trypsin inhibitor cti, by Prolytix (1 mentions) Collagen type 1, by Chrono-Log (1 mentions)

2 protocols using h gly pro arg pro oh gprp

1

Evaluating Fibrin Formation and Platelet Function

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The following reagents were obtained: Sigmacote (Millipore Sigma, Cat# SL2-100ML), collagen (type I; Chrono-Log, Cat# 385), Dade Innovin prothrombin time reagent (Siemens, Cat# B4212-40), corn trypsin inhibitor (CTI; Haematologic Technologies, Cat# CTI-01), fluorescently labeled fragment derived from α2-AP (Ac-GNQEQVSPLTLLKW-C[IAF], α2-APF, CPC Scientific), antihuman CD61 antibody (BD Biosciences, Cat# 555754), Alexa Fluor 647 Conjugated Human Fibrinogen (Life Technologies, Cat# F35200), H-Gly-Pro-Arg-Pro-OH (GPRP; Millipore Sigma, Cat# 03-34-0001), Phe-Pro-Arg-chloromethylketone (PPACK; Haematologic Technologies, Cat# FPRCK-01), 1,3,4,5-tetramethyl-2-([2-oxopropyl]thio) imidazolium chloride (T101; Zedria GmbH), Recombinant Human Tissue Plasminogen Activator Protein (tPA; Abcam, Cat# ab92637), and rhosin (Rho inhibitor; Millipore Sigma, CAS 1173671-63-0).
Liu Y., Crossen J., Stalker T.J, & Diamond S.L. (2023). Fluorescent peptide for detecting factor XIIIa activity and fibrin in whole blood clots forming under flow. Research and Practice in Thrombosis and Haemostasis, 8(1), 102291.
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2

Platelet Activation Signaling Assay

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Reagents were obtained as follows: anti-human CD61 antibody (BD Biosciences, San Jose, CA. Cat#: 555754), Alexa Fluor 647–conjugated human fibrinogen (Life Technologies, Grand Island, NY. Cat#: F35200), Alexa Fluor 488 phospho-Src (Tyr418) polyclonal antibody (ThermoFisher Scientific, Waltham, MA. Cat#: 44–660A1), Dade Innovin prothrombin time (PT) reagent (Siemens, Malvern, PA. Cat#: B4212–40), collagen (type I; Chrono-Log, Havertown, PA. Cat#: 385), Sigmacote® (Millipore Sigma, Burlington, MA. Cat#: SL2–100ML), H-Gly-Pro-Arg-Pro-OH (GPRP; Millipore Sigma, Burlington, MA. Cat#: 03-34-0001), dasatinib (Selleckchem, Houston, TX. Cat#: S1021), GS-9973 (entospletinib) (Selleckchem, Houston, TX. Cat#: S7523), Alexa Fluor 488-conjugated annexin V (ThermoFisher Scientific, Waltham, MA. Cat#: A13201), GR144053 (Tocris Biosciences, Bristol, UK. Cat#: 1263), Phe-Pro-Arg-chloromethylketone (PPACK, Haematologic Technologies, Essex Junction, VT. Cat#: FPRCK-01) and corn trypsin inhibitor (CTI, Haematologic Technologies, Essex Junction, VT. Cat#: CTI-01).
Zhang Y, & Diamond S.L. (2020). Src family kinases inhibition by dasatinib blocks initial and subsequent platelet deposition on collagen under flow, but lacks efficacy with thrombin generation.. Thrombosis research, 192, 141-151.
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