3.0 t achieva

Using the same 3.0-T MRI scanner (Philips 3.0 T Achieva; Philips Healthcare, Andover, MA, USA), we acquired 3D T1 turbo field echo MRI and fluid-attenuated inversion recovery (FLAIR) images from all participants as previously described [30 (link)]. Imaging parameters were as follows: T1-weighted—slice thickness, 1 mm; repetition time (TR)/echo time (TE), 4.6/9.9 ms; flip angle, 88 degrees; field of view, 24 × 24 cm; and matrix size, 240 × 240 pixels; and FLAIR—axial slice thickness, 2 mm; no gap; TR/inversion time/TE, 11,000/2800/125 ms, respectively; field of view, 24 × 24 cm; and matrix size, 256 × 256 pixels.

All participants underwent standardized T2, 3-dimensional T1 turbo field echo images, 3-dimensional (3D) fluid-attenuated inversion-recovery (FLAIR), and T2×-weighted gradient echo (GRE)-MRIs at Samsung Medical Center using a 3.0T MRI scanner (Philips 3.0T Achieva; Philips Healthcare, Andover, MA, USA) [31 (link)]. The following parameters were used for the T2* GRE images: axial slice thickness 5.0 mm, inter-slice thickness 2 mm, repetition time (TR) 669 ms, echo time (TE) 16 ms, flip angle 18°, and matrix size 560 × 560 pixels. We acquired 3D T1 images with the following parameters: sagittal slice thickness 1.0 mm, over contiguous slices with 50% overlap, TR 9.9 ms, TE 4.6 ms, flip angle 8°, and matrix size 240 × 240 pixels, reconstructed to 480 × 480 over a field of view of 240 mm. 3D FLAIR images were obtained with the following parameters: axial slice thickness 2 mm, no gap, TR 11,000 ms, TE 125 ms, flip angle 90°, and matrix size 512 × 512 pixels.

We acquired standardized 3D T1 turbo field echo images and 3D FLAIR images from all of the patients using the same 3.0 T MRI scanner (Philips 3.0 T Achieva; Philips Health care). Briefly, the 3D T1 MR images were set to the following parameters: sagittal slice thickness, 1.0 mm, over contiguous slices with 50% overlap; no gap; a repetition time of 9.9 ms; an echo time of 4.6 ms; a flip angle of 8°; and a matrix size of 240 × 240 pixels reconstructed to 480 × 480 over a field of view of 240 mm. The 3D FLAIR image parameters included the following: axial slice thickness of 2 mm; no gap; repetition time of 11,000 ms; echo time of 125 ms; flip angle of 90°; and matrix size of 512 × 512 pixels.