Dextran t 10

Example 1

Under ambient conditions, a 1 M cerium nitrate (Aldrich, 99%) solution (2.17 g in 5 ml of water) was mixed with a 1.0M Dextran T-10 (Sigma) (5 g in 10 ml of water) to form mixture (I) comprising a plurality of ceria nanoparticles.

Alternately, if preparing polyacrylic acid (PAA) coated nanoceria, 0.5 M solution of polyacrylic acid (PAA) (Sigma) is used instead of 1.0M Dextran T-10 to form mixture (I).

Under continuous stirring, the mixture (I) is then added dropwise to 30 ml of 29% ammonium hydroxide solution (Fischer, USA) forming mixture (II). Mixture (II) is then stirred continuously for 24 hours. After 24 hours of stirring, the solution turns from a light yellow to a deep brown color indicating the formation of stabilized dextran or PAA coated-nanoceria. The preparation is centrifuged at a rate of 4000 rpm for two 30-minute cycles to settle down any debris and large agglomerates. The supernatant solution is then purified by removal of free polyacrylic acid (PAA) or dextran by ultrafiltration using a 30 K Amicon cell (Millipore Inc.).

Example 1

Under ambient conditions, a 1 M cerium nitrate (Aldrich, 99%) solution (2.17 g in 5 ml of water) was mixed with a 1.0 M Dextran T-10 (Sigma) (5 g in 10 ml of water) to form mixture (I) comprising a plurality of ceria nanoparticles.

Alternately, if preparing polyacrylic acid (PAA) coated nanoceria, 0.5 M solution of polyacrylic acid (PAA) (Sigma) is used instead of 1.0 M Dextran T-10 to form mixture (I).

Under continuous stirring, the mixture (I) is then added dropwise to 30 ml of 29% ammonium hydroxide solution (Fischer, USA) forming mixture (II). Mixture (II) is then stirred continuously for 24 hours. After 24 hours of stirring, the solution turns from a light yellow to a deep brown color indicating the formation of stabilized dextran or PAA coated-nanoceria. The preparation is centrifuged at a rate of 4000 rpm for two 30-minute cycles to settle down any debris and large agglomerates. The supernatant solution is then purified by removal of free polyacrylic acid (PAA) or dextran by ultrafiltration using a 30 K Amicon cell (Millipore Inc.).