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Discovery mr750 3.0 tesla scanner

Manufactured by GE Healthcare

The Discovery MR750 3.0 Tesla scanner is a magnetic resonance imaging (MRI) system designed and manufactured by GE Healthcare. It operates at a magnetic field strength of 3.0 Tesla, allowing for high-quality imaging of the human body.

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6 protocols using discovery mr750 3.0 tesla scanner

1

High-Resolution Multimodal Brain Imaging Protocol

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Data were acquired using a GE Discovery MR750 3.0 Tesla scanner with a standard adult‐sized coil (Milwaukee, WI). A full‐brain high‐resolution T1 SPGR PROMO scan was acquired that is used in preprocessing (TR = 7,000 ms, TE = 2,900 ms, flip angle = 8°, FOV = 25.6 cm, slice thickness = 1 mm, 208 sagittal slices; matrix = 256x256). Before the MID task, a fieldmap was acquired using spin‐echo EPI (TR = 7,400 ms, TE = 80 ms, FOV = 21.6 cm, 90x90 matrix) with opposite phase encoding polarity (A➔P, P➔A). Two functional T2*‐weighted blood‐oxygen‐level‐dependent (BOLD) MID runs were acquired in the axial plane following structural and a face task using a multiband EPI sequence (MB factor = 6) of 60 contiguous axial 2.4 mm slices (TR = 800 ms, TE = 30 ms, flip angle = 52°, FOV = 21.6 cm, 90x90 matrix, volumes = 407).
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2

Resting-State fMRI Acquisition Protocol

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All neuroimaging was conducted using a Discovery MR750 3.0 Tesla scanner with a 32-channel head-coil (General Electric). High-resolution T1-weighted images were collected for coregistration using the following parameters: field of view (FOV), 240 mm; matrix, 256 × 224; slice thickness, 1 mm; 150 slices; repetition time (TR)/echo time (TE), 8.2/3.2 seconds, flip angle, 12o; voxel size, 1 × 0.938 × 0.938 mm. Participants underwent an 8-minute eyes-open resting-state scan, during which 240 volumes were acquired using the following parameters: FOV, 22.4 mm; matrix, 64 × 64; slice thickness, 3.5 mm; 41 sagittal slices; TR/TE, 2000/25 milliseconds; flip angle, 77°; voxel size, 3.5 × 3.5 × 3.5 mm.
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3

Functional MRI Assessment of Resting-State Brain

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We conducted functional magnetic resonance imaging (fMRI) scans to all subjects with GE Discovery MR750 3.0 Tesla scanner at the Magnetic Resonance Imaging Research Center, Institute of Psychology, Chinese Academy of Sciences. High-resolution structural 3D T1-weighted images were acquired by the gradient recalled echo sequence with the following parameters: TI = 450 ms, receiver bandwidth = 31.25, matrix = 256 × 256, field of view (FOV) = 240 mm, slice thickness = 1.5 mm, and flip angle = 12°. Resting-state functional MRI images were obtained using a gradient-recall echo-planar imaging (GRE-EPI) pulse sequence with the following parameters: repetition time = 2000 ms, echo time = 30 ms, FOV = 220 mm × 220 mm, matrix = 64 × 64, flip angle = 70°, number of slices = 33, and slice thickness = 4 mm with no gap. During the fMRI scanning, all of the subjects were required to stay awake with their eyes closed, relax their minds and keep their bodies still. Each functional run lasted for 10 min.
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4

3T Structural MRI and Cortical Surface Reconstruction

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Structural MRI images were acquired with a General Electric Discovery MR750 3.0 Tesla Scanner (GE Healthcare, Milwaukee, WI) at the UCSD Center for fMRI, using a Nova Medical 32 channel head coil. Whole-head structural images were acquired with a standard Fast Spoiled Gradient Recalled (FSPGR) T1-weighted sequence (TR = 8.136 ms; TE = 3.172 ms; flip angle = 8°; FOV = 25.6 cm; acquisition matrix = 256 × 256; voxel size = 1 mm3; slices: 172; total duration: 5 min). Each participant’s cortical surface was reconstructed from these images using Freesurfer (Dale et al., 1999 (link), Fischl et al., 1999a (link)) and served to constrain inverse solution estimates. For forward calculations, inner skull surface was derived from segmented MRI data and used for a boundary element model of the volume conductor. For group-wise analyses, the reconstructed individual surfaces were morphed into an average representation by aligning their sulcal-gyral patterns (Fischl et al., 1999b (link)) and decimated, defining the solution space with 5124 free-rotating dipoles spaced ∼ 7 mm apart.
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5

High-resolution brain imaging protocol

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Data were acquired using a GE Discovery MR750 3.0 Tesla scanner with a standard adult-sized coil (Milwaukee, WI). A full-brain high-resolution T1 SPGR PROMO scan was acquired for registration (TR = 7,000 ms, TE = 2,900 ms, flip angle = 8°, FOV = 25.6 cm, slice thickness = 1 mm, 208 sagittal slices; matrix = 256 × 256). Next, two functional T2*-weighted BOLD MID runs were acquired in the axial plane using a multiband EPI sequence (MB factor = 6) of 60 contiguous axial 2.4 mm slices (TR = 800 ms, TE = 30 ms, flip angle = 52°, FOV = 21.6 cm, 90 × 90 matrix, volumes = 407). A field map was also acquired right before the task using spin-echo EPI (TR = 7,400 ms, TE = 80 ms, FOV = 21.6 cm, 90 × 90 matrix) with opposite phase encoding polarity (A → P, P → A).
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6

Brain Imaging Using 3T MRI

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Scanning took place on the GE Discovery MR 750 3.0 Tesla scanner (General Electric, Milwaukee, WI) using a 32‐channel head coil. Functional images were acquired using a T2*‐weighted gradient‐echo echo‐planar imaging sequence to produce 40 continuous transaxial slices with a thickness of 3.5 and 0.5 mm gap, respectively, covering the entire cerebrum and cerebellum (repetition time [TR] = 2,300 ms; echo time [TE] = 30 ms; flip angle [FA] = 81°; field of view [FOV] = 192 mm; 64 × 64 matrix; voxel dimension = 3.0 × 3.0 mm; 201 acquisitions). During the scan, the participants were instructed to close their eyes, remain awake, and think of nothing in particular.
We acquired high‐resolution structural whole‐brain images using a 3D T1‐weighted fast spoiled‐gradient recalled imaging sequence (TR = 6.38 ms; TE = 1.99 ms; FA = 11°; FOV = 256 mm; 256 × 256 matrix; 172 slices; voxel dimension = 1.0 × 1.0 × 1.0 mm).
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