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Gsk4716

Manufactured by Abcam
Sourced in United Kingdom

GSK4716 is a selective, orally bioavailable glucocorticoid receptor (GR) modulator. It acts as a partial agonist on the GR receptor.

Automatically generated - may contain errors

2 protocols using gsk4716

1

ACEA and 2-AG Evaluation Protocol

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ACEA (arachidonyl-2′-chloroethylamide) and 2-AG (2-arachidonyl glycerol) were purchased from Tocris Bioscience (Ellisville, MO, USA). GSK4716 was purchased from Abcam (Abcam, Cambridge, UK). All chemicals were dissolved in the recommended solvent.
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2

Synthesis and Dissolution of GSK Compounds

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GSK5182 was synthesized at Kyungpook National University (Daegu, Republic of Korea) and DGMIF (Daegu-Gyeongbuk Medical Innovation Foundation, Daegu, Republic of Korea), as described previously [10 (link),34 (link),43 (link),44 (link)], and dissolved in 30% polyethylene glycol 400 (PEG400, USB, Cleveland, OH, USA) or DMSO (MilliporeSigma, St. Louis, MO, USA). GSK4716 was purchased from Abcam (Cambridge, UK). 4-hydroxytamoxifen (4-OHT) and bisphenol A (BPA) were purchased from MilliporeSigma (St. Louis, MO, USA). XCT790 was purchased from TOCRIS (Bristol, UK)
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