For ALFA, MRI scans were obtained with a 3T scanner (Ingenia CX, Philips, Amsterdam, Netherlands) and included a T1-weighted Turbo Field Echo sequence (repetition time = 10 ms, echo time = 5 s, flip angle = 8 and voxel size = 0.75 mm3 isotropic) and a diffusion weighted imaging (DWI) protocol (repetition time = 9 ms, echo time = 90 ms, 8 b0 volumes, 64 b = 1000 s/mm2 volumes and voxel size = 2.2 mm3 isotropic). For PREVENT, a T1-weighted magnetization prepared rapid gradient echo scan was acquired (repetition time = 2.3 s, echo time = 2.98 ms, flip angle = 9, and voxel size = 1 mm3 isotropic) on 3T Siemens scanners: Prisma fit (Oxford), Prisma fit (Cambridge), Verio (West London) and Skyra (Dublin and Edinburgh). The DWI protocol in PREVENT was as follows: repetition time = 11 s 700 ms, echo time = 90 ms, 1 b0 volumes, 64 b = 1000 s/mm2 volumes, flip angle = 90, and voxel size = 2 mm3 isotropic.
Prisma fit
Manufactured by Siemens
Sourced in Germany
Prisma Fit is a piece of laboratory equipment designed for spectroscopic analysis. It functions as a spectrometer, capable of measuring the absorption or emission spectra of samples. The core purpose of the Prisma Fit is to provide precise and accurate spectroscopic data for research and analytical applications.
Automatically generated - may contain errors
Lab products found in correlation
Tim trio, by Siemens (14 mentions)
Magnetom trio, by Siemens (5 mentions)
Skyrafit, by Siemens (4 mentions)
Ingenia cx, by Philips (3 mentions)
Matlab, by MathWorks (3 mentions)
Magnetom vida, by Siemens (2 mentions)
Ingenia, by Philips (2 mentions)
Gadovist, by Bayer (2 mentions)
Magnetom skyra, by Siemens (2 mentions)
32 channel receive only head coil, by Siemens (2 mentions)
Prisma, by Siemens (2 mentions)
Achieva scanner, by Philips (1 mentions)
Braincap mr, by Brain Products (1 mentions)
Geodesic eeg system, by Electrical Geodesics (1 mentions)
Ingenia, by Siemens (1 mentions)
Magnetom aera, by Siemens (1 mentions)
Signa hdxt, by GE Healthcare (1 mentions)
Ingenia elition, by Philips (1 mentions)
Magnetom lumina, by Siemens (1 mentions)
Discovery mr750w, by GE Healthcare (1 mentions)
113 protocols using prisma fit
1
MRI and Diffusion Imaging Protocols for ALFA and PREVENT
2
Multimodal MRI Acquisition Protocols
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For the NCANDA study, T1-weighted images were collected in the sagittal plane using a 3 T General Electric (GE) Discovery MR750 with an 8-channel head coil (TR = 5.904 ms, TI = 400 ms, TE = 1.932 ms, flip angle = 11°, voxel size = 1.2 × 0.9375 × 0.9375 mm, 146 slices), a 3 T Siemens TIM TRIO with a 12-channel head coil, or 3 T Siemens PRISMA FIT with a 20-channel head and neck coil (TR = 1900 ms, TI = 900 ms, TE = 2.92 ms, flip angle = 9°, voxel size = 1.2 × 0.9375 × 0.9375 mm, 160 slices).
For the AR study, T1-weighted images were collected in the sagittal plane using a 3 T Siemens TIM TRIO with a 12-channel head coil or PRISMA FIT with a 20-channel head and neck coil (TR = 2300 ms, TI = 900 ms, TE = 3.58–3.61 ms, flip angle = 10°, voxel size = 1.1 × 1 × 1 mm, 160 slices).
For the AR study, T1-weighted images were collected in the sagittal plane using a 3 T Siemens TIM TRIO with a 12-channel head coil or PRISMA FIT with a 20-channel head and neck coil (TR = 2300 ms, TI = 900 ms, TE = 3.58–3.61 ms, flip angle = 10°, voxel size = 1.1 × 1 × 1 mm, 160 slices).
3
Multi-Modal Imaging with 3T MRI and EEG
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Data were collected using two different clinical 3 Tesla MRI scanners from two different vendors: A Philips Achieva scanner (Philips, Best, The Netherlands) equipped with a 32 channel RF head array coil and a Siemens Prisma Fit (Siemens, Erlangen, Germany) scanner equipped with a 64 channel RF head array coil. The scanners were located respectively at Glostrup and Blegdamsvej campus of Rigshospitalet, Copenhagen, Denmark; The Philips Achieva scanner was equipped with a 32- and a 64-channel MR Cap (BrainCapMR, Brain Products GmbH, Munich, Germany), which consisted of 63 EEG electrodes, 1 external ECG electrode, 1 ground (AFz), and, 1 reference electrode (FCz). The Siemens Prisma scanner was equipped with a Geodesic EEG System (Electrical Geodesics, Inc., Eugene, OR) with 256 EEG channels, 2 external ECG electrodes and 1 reference electrode (Cz).
Phantom measurements were performed using a spherical daily quality assurance phantom provided by the manufacturers.
Phantom measurements were performed using a spherical daily quality assurance phantom provided by the manufacturers.
4
Neuroimaging and Neurodegeneration Assessment Protocol
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Patients underwent neuroimaging assessments using either 1.5T MRI scanner (Philips Ingenia) or 3T Siemens Prisma Fit (Siemens, Erlangen, Germany). T1-weighted and FLAIR scans were used for visual rating of scans. Subject FLAIR scans were visually rated based on the modified Fazekas scale for white matter hyperintensity (WMH) severity [27 ]. Patients were classified as having confluent WMH and non-confluent WMH based on the Staals criteria [28 (link)]: a WMH rating of 3 in either periventricular and/or a rating of 2 or 3 in deep white matter regions in either hemisphere were assigned as confluent. Raters doing the MRI visual ratings were blinded to diagnosis and clinical information.
The neurodegeneration (N) profile was assigned based on the medial temporal lobe atrophy (MTA) scores based on the Schelten’s scale [29 (link)].
The neurodegeneration (N) profile was assigned based on the medial temporal lobe atrophy (MTA) scores based on the Schelten’s scale [29 (link)].
5
3T MRI Brain Imaging Protocol
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Images were acquired using a 3 T MRI Siemens Trio scanner updated to Prisma Fit with a standard 32-channel head coil during data collection. The image sequence is a T2*-weighted pulse sequence (184 volumes; TR = 2200 ms; TE = 30 ms; matrix = 64 × 64 voxels; FOV = 210 mm; flip angle = 90°; slice thickness = 3 mm; acquisition = 36 slides in the axial plane with a distance factor of 25% to scan the whole brain). A high-resolution structural image was obtained using a 3D T1-weighted imaging sequence using an MP-RAGE (TFE) sequence (TR = 2300 ms; TE = 2.98 ms; 192 slices; matrix = 256 × 256; voxel size = 1 × 1 × 1 mm3; FOV = 256 mm).
6
Brain MRI Protocol for Neuroimaging Research
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All patients selected according to the study criteria underwent brain MRI (MAGNETOM Aera, Symphony, Skyra, Skyra fit, Prisma fit, Vida or Verio, all Siemens Healthcare, Erlangen, Germany) at 1.5-Tesla (14%) or 3-Tesla (86%) in the Department of Diagnostic and Interventional Radiology of our institution. The MRI protocol included a 3D sagittal T1 magnetization prepared rapid gradient echo (T1-MPRAGE) sequence using the 1.5 T and 3 T Alzheimer’s disease neuroimaging initiative (ADNI) protocols [13 (link)–15 (link)] and a 2D axial T2 spin echo (T2-SE) sequence (TR 5000 ms, TE 77 ms, flip angle 150°, matrix 256 × 240, slice thickness 3 mm, slice number 43, voxel size 0.5 × 0.5 × 3 mm3).
7
Multi-Modal MRI Acquisition Protocol
8
Multiparametric MRI Protocol for Liver Imaging
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MRI exams were performed using 3.0-Tesla (T) systems (Skyra, Verio, Prisma Fit, Magnetom Lumina, or Magnetom Vida, Siemens Healthineers, Erlangen, Germany; Achieva, Ingenia, Ingenia CX, or Ingenia Elition, Philips Healthcare, Best, Netherlands; and Signa HDxt, Signa Architect, or Discovery MR750w, GE Healthcare, Waukesha, WI). The scan protocol included the acquisition of dual-echo T1-weighted gradient-echo images (in- and opposed-phase), T1-weighted three-dimensional gradient-echo images with dynamic contrast enhancement, navigator-triggered single- or multi-shot T2-weighted images, and diffusion-weighted images (DWI) at various b-values. Dynamic T1-weighted imaging was performed before and after the administration of either ECA (gadobutrol, Gadovist, Bayer Pharma AG, Berlin, Germany) or HBA (gadoxetate disodium, Primovist, Bayer Pharma AG). Arterial phase scanning was initiated using the test bolus or bolus tracking technique, after which PVP and DP images were obtained using ECA-MRI. For HBA-MRI, PVP, DP, and 20-minute delayed HBP images were obtained using HBA-MRI. Detailed parameters of the MRI sequences are listed in S1 Table .
9
Functional MRI Imaging on 3T Siemens Prisma
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Participants were scanned on a 3-Tesla Siemens Prisma Fit (Siemens, Erlangen, Germany) MRI Scanner. fMRI data during the task were acquired in 1 single run of 4:29 minutes with a field-of-view (FOV) = 208 mm2, slice thickness = 2 × 2 × 2 mm, TR = 1300 milliseconds, TE = 32.60 milliseconds, and flip angle = 70 degrees. A high-resolution T1-weighted MP-RAGE distortion corrected anatomical image was also acquired (duration of 6:07 minutes) in ascending order with a FOV = 256 mm2, slice thickness = 1 × 1 × 1 mm, TR = 2300 milliseconds, TE = 2.96 milliseconds, and flip angle = 9 degrees. A Siemens Prisma Fit 64 channel head coil was used.
10
MRI Evaluation of Vessel Wall Abnormalities in Suspected Vasculitis
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The indication to perform an MRI examination in case of suspected vasculitis was set by the treating physician based on clinical and laboratory findings. The MR examination was performed in the supine position using a 3-Tesla MRI (Prisma fit; Siemens Healthineers, Forchheim, Germany). The contrast agent was administered via peripheral venous access (Gadovist™ [EU]). Depending on the region to be examined, a dedicated body coil was placed (e.g., a 16-channel body coil).
All MRI examinations contained basic fat-suppressed T1-weighted sequences, T2-weighted turbo spin echo sequences, as well as routinely included "dark-blood sequences" ("db sequence", navigated 3D turbo spin echo) for a better assessment of mural inflammation. All images were acquired in axial orientation except for T2-weighted sequences, which were also performed in the coronal plane.
The following data were evaluated: date, region, affected vessels, edema or thickening of the vessel wall, diameter of the vessel wall and lumen, fluid deposition around the vessel, and the presence of aneurysms. The vessel wall was measured at the thickest point in the axial plane, whereas the wall of the aortic arch was assessed in the coronal plane.
All MRI examinations contained basic fat-suppressed T1-weighted sequences, T2-weighted turbo spin echo sequences, as well as routinely included "dark-blood sequences" ("db sequence", navigated 3D turbo spin echo) for a better assessment of mural inflammation. All images were acquired in axial orientation except for T2-weighted sequences, which were also performed in the coronal plane.
The following data were evaluated: date, region, affected vessels, edema or thickening of the vessel wall, diameter of the vessel wall and lumen, fluid deposition around the vessel, and the presence of aneurysms. The vessel wall was measured at the thickest point in the axial plane, whereas the wall of the aortic arch was assessed in the coronal plane.
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