The MRI image acquisition was performed at the Radiology and Imaging Sciences department of the National Institutes of Health Clinical Center. All abdominal scans in this study were acquired on a 3T whole-body MRI scanner (Philips Medical Systems, Best, The Netherlands) using a SENSE XL Torso receiving coil for signal reception. A standard three-dimensional two-point Dixon T1-weighted imaging sequence was prescribed with typical acquisition parameters of repetition time 3.41 ms, echo times 1.19 ms and 2.37 ms, flip angle 10°, pixel bandwidth 1965 Hz/pixel, percent phase field of view 72.2, field of view 317 mm × 317 mm, acquisition matrix 212 × 212, and reconstruction image matrix 288 × 288. Two image series were acquired to cover the L2–L3 and L4–L5 spine segments separately.
3t whole body mri scanner
Manufactured by Philips
Sourced in Netherlands
The Philips 3T whole-body MRI scanner is a medical imaging device that uses a powerful magnetic field and radio waves to create detailed images of the body's internal structures. It is designed to provide high-resolution, three-dimensional images of the entire body. The 3T field strength allows for faster scanning and improved image quality compared to lower-field MRI systems.
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Lab products found in correlation
6 protocols using 3t whole body mri scanner
1
3T MRI Acquisition of Abdominal Scans
2
Functional MRI Acquisition Protocol
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Functional images were acquired at the Kiel University hospital using a 3 T whole-body MRI scanner (Achieva; Philips, Best, the Netherlands) equipped with an 8-channel head coil. An IFIS system (Invivo, Gainesville, FL, USA) provided with E-Prime software (Psychology Software Tools, Inc., Sharpsburg, PA, USA) was used for stimulus presentation and response recording.
We performed a whole-brain echo planar imaging (EPI) to measure regional changes in the blood oxygen level-dependent (BOLD) signal. The EPI sequence consisted of 635 volumes with 38 axial slices acquired parallel to the anterior–posterior plane with the following acquisition parameters: Slice thickness 3.0 mm, inter-slice gap of 0.3 mm, TR 2500 ms; TE 36.4 ms; FOV 216 × 216 × 125.1 mm3; matrix 64 × 64; flip angle 90°. The resulting voxel size was 3.38 × 3.38 × 3.29 mm.
For normalization to the Montreal Neurological Institute (MNI) standard space and radiological diagnostics a 3-dimensional (3D) T1-weighted gradient echo MRI scan with sagittal volume excitation was acquired from each participant with the following parameters: TR 7.8 ms; TE 3.6 ms; TI 800 ms; flip angle 8°; FOV 160 × 240 × 240 mm3; 160 slices with an image matrix and a scan resolution of 240 × 224 voxels and a reconstruction matrix of 256 × 256 voxels yielding in final voxel size of 1 × 0.94 × 0.94 mm3.
We performed a whole-brain echo planar imaging (EPI) to measure regional changes in the blood oxygen level-dependent (BOLD) signal. The EPI sequence consisted of 635 volumes with 38 axial slices acquired parallel to the anterior–posterior plane with the following acquisition parameters: Slice thickness 3.0 mm, inter-slice gap of 0.3 mm, TR 2500 ms; TE 36.4 ms; FOV 216 × 216 × 125.1 mm3; matrix 64 × 64; flip angle 90°. The resulting voxel size was 3.38 × 3.38 × 3.29 mm.
For normalization to the Montreal Neurological Institute (MNI) standard space and radiological diagnostics a 3-dimensional (3D) T1-weighted gradient echo MRI scan with sagittal volume excitation was acquired from each participant with the following parameters: TR 7.8 ms; TE 3.6 ms; TI 800 ms; flip angle 8°; FOV 160 × 240 × 240 mm3; 160 slices with an image matrix and a scan resolution of 240 × 224 voxels and a reconstruction matrix of 256 × 256 voxels yielding in final voxel size of 1 × 0.94 × 0.94 mm3.
3
MRI Characterization of Scaffolds
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For MRI, the scaffolds were embedded in 1% (w/v) agarose phantoms, and measured with a clinical 3T whole-body MRI scanner (Philips Achieva, Best, Netherlands). T2 weighted imaging (T2WI), T2 mapping, and T2∗ mapping sequences were performed. T2WI were acquired using a multi-slice, multi-shot spin-echo sequence [time of repetition (TR) = 3328 ms, time of echo (TE) = 80 ms, field of view (FOV) = 80 mm × 40 mm, matrix size = 64 × 64, and slice thickness = 1 mm]. For transverse (T2) relaxometry, images were acquired at 6 echo times [TE range 8–48 ms] using spin-echo sequences [TR = 1500 ms, FOV = 40 mm × 40 mm, reconstruction matrix = 288, slice thickness = 1 mm]. For transverse (T2∗) relaxometry, images at 6 echo times [TE range 5.4–35.1 ms] were acquired by using a multi-shot, multi-slice fast-field gradient-echo sequence [TR = 804 ms, FOV = 40 mm × 40 mm, reconstruction matrix = 112, slice thickness = 0.8 mm, and flip angle = 45°]. T2 and T2∗ relaxation times (R2 and R2∗) were calculated using the Imalytics Preclinical Software (Philips Technology GmbH, Aachen, Germany).
4
MRI-Based Muscle Fiber Typology Estimation
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Muscle carnosine content was measured by 1 H-MRS in the GM of each participant's right limb to estimate muscle fiber typology. We chose to estimate the muscle fiber typology of the GM because (i) we can measure carnosine reliably in this muscle, (ii) carnosine content in the GM muscle has been positively correlated with the percentage area occupied by Type II muscle fibers ( 26 ), and (iii) the GM makes a substantial contribution to force and power production during running and jumping ( 29,30 ). This suggests that the fiber composition of the GM may be meaningful in the context of sprinting and jumping. 1 H-MRS measurements were performed on a 3-T whole body MRI scanner (Philips Medical Systems Best, The Netherlands). Participants were lying in a supine position, while their lower leg was fixed in a spherical knee-coil. All the spectra were acquired using a singlevoxel point-resolved spectroscopy with the following parameters: repetition time, 2000 ms; echo time, ~40 ms; number of excitations, 128 (carnosine) and 16 (water); spectral bandwidth, 2048 Hz; and acquisition time, 4 min 16 s (carnosine) and 32 s (water). The voxel size was 40 × 15 × 20 mm. Spectral data analysis was carried out using jMRUI (version 6.0), with carnosine peaks fitted and expressed relative to the internal water signal.
Carnosine content (mM) was calculated using following formula:
Carnosine content (mM) was calculated using following formula:
5
Structural Brain Imaging Protocol
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All imaging was performed on a Philips 3T whole-body MRI scanner (Philips Medical Systems, Bothell, WA). First, a wholebrain 3-dimensional T1-weighted structural image was acquired with the following scan parameters: voxel size = 0.8 mm A full description of the preprocessing steps can be found in the Supplement.
6
Imaging the Calf Muscles with MRI
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Images were acquired on a 3T wholebody MRI scanner (Achieva TX, Philips Healthcare) using the body coil for transmission and an 8-channel knee coil as the receiver. In 1 patient with SLE and 2 healthy controls, the diameter of the lower leg was too large for the knee coil, and for these participants a 2-channel flex-M receiver coil was used. The imaging volume was centered at the thickest part of the right calf, with the subject in supine position.
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