Chloroplatinic acid

Manufactured by Maclin Biochemical Technology

Sourced in China

Chloroplatinic acid is a chemical compound with the formula H2PtCl6. It is a yellow to orange crystalline solid that is soluble in water. Chloroplatinic acid is commonly used as a catalyst in various chemical reactions.

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Close spelling variants of this product

Chloroplatinic acid hexahydrate (6 citations) Chloroplatinic acid (H2PtCl6) (2 citations)

5 protocols using chloroplatinic acid

Electrochemical Biosensor for Acetylcholinesterase

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Chloroauric acid trihydrate (HAuCl₄, 4~50% Au basis), iron (II, III) oxide (MBs,100–200 nm, 5 mg mL⁻¹), chloroplatinic acid (H₂PtCl₆, 99.9%), single-layer graphene oxide dispersion (2 mg mL⁻¹, dispersion in H₂O), acetylthiocholine iodide (ACH), acetylcholinesterase (AChE, 200 U g⁻¹), and choline oxidase (CHOx, 8–20 U mg⁻¹) were purchased from Shanghai Macklin Biochemical Co., Ltd. (Shanghai, China). Trisodium citrate dihydrate (C₆H₅Na₃O₇·2H₂O), ethylenediaminetetraacetic acid disodium salt (C₁₀H₁₄N₂Na₂O₈), citric acid monohydrate (C₆H₁₀O₈), glycerol (C₃H₈O₃), and dimethyl sulfoxide (DMSO, C₂H₆OS) were bought from Xilong Scientific Co., Ltd. (Guangzhou, China).
A 5500 UV-vis spectrometer (Shanghai Yuanxi Instrument Co., Ltd., Shanghai, China) was used to obtain UV-vis absorption spectra. All electrochemical measurements were performed on a CHI 440C (CH Instruments, Inc., Dellas, TX, USA) electrochemical workstation with a three-electrode system (a glassy carbon electrode, a platinum wire, and Ag/AgCl electrode were used as working, counter, and reference electrode, respectively).

Ji C., Tang X., Wen R., Xu C., Wei J., Han B, & Wu L. (2024). A Multienzyme Reaction-Mediated Electrochemical Biosensor for Sensitive Detection of Organophosphorus Pesticides. Biosensors, 14(2), 62.

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Fabrication of Cholesterol-Grafted PLLA Scaffolds

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Medical-grade PLLA (Mη = 1 × 10⁵ g/mol) was supplied by Daigang Biomaterial Co. (Jinan, China). Cholesterol (purity ≥ 99.0%) was purchased from Aiwang Chemical Technology Co. (Shanghai, China). Undecylenic acid, chloroplatinic acid (H₂PtCl₆▪6H₂O), and polymethylhydrogensiloxane (PMHS, Mn = 697) were purchased from Shanghai Macklin Biochemical Co. (Shanghai, China). Dicyclohexylcarbodiimide (DCC), 4-dimethylaminopyridine (DMAP), N,N-dimethylformamide, toluene, dichloromethane (DCM), hydrochloric acid (HCl), sodium hydroxide (NaOH), sodium bicarbonate (NaHCO₃), anhydrous magnesium sulfate (MgSO₄), methanol, and ethanol were supplied by Sinopharm Chemical Reagent Co. (Shenyang, China). SBF (1.5 × SBF) was obtained from Xinhua Luyuan Technology Co., Ltd. (Beijing, China).

Zhan Y., Deng B., Wu H., Xu C., Wang R., Li W, & Pan Z. (2021). Biomineralized Composite Liquid Crystal Fiber Scaffold Promotes Bone Regeneration by Enhancement of Osteogenesis and Angiogenesis. Frontiers in Pharmacology, 12, 736301.

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Highly Sensitive Enzymatic Biosensor

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All reagents were not purified further before use. Methylbenzene, hydrochloric acid (HCl), lysine (Lys), arginine (Arg), titanium tetrachloride (TiCl₄), tetrabutyltitanate, gold (III) chloride (HAuCl₄·3H₂O), leucine (Leu), cysteine (Cys), proline (Pro), glycine (Gly), barium hydroxide octahydrate (Ba(OH)₂·8H₂O), formic acid, ethylene diamine tetraacetic disodium (EDTA−2Na), chloroplatinic acid (H₂PtCl₆), 3,3′,5,5′−tetramethylbenzidine (TMB, ≥99%), L−histidine (L−His), glutathione (GSH), glutamic acid (Glu), and fetal bovine serum were purchased from Macklin Biochemical Co., Ltd. (Shanghai, China). Sodium borohydride (NaBH₄), disodium hydrogen phosphate (Na₂HPO₄), p−Benzoquinone (p−BQ), isopropanol (IPA), potassium nitrate (KNO₃), citric acid, ascorbic acid (AA), and sodium nitrate (NaNO₃) were purchased from Sinopharm Chemical Reagents Co., Ltd. (Shanghai, China).

Liao Y., He Y., Zhang B., Ma Y., Xu R., Zhao M, & Cui H. (2024). Using the Photo–Piezoelectric Effect of AuPt@BaTiO3 Oxidase Mimetics for Colorimetric Detection of GSH in Serum. Sensors (Basel, Switzerland), 24(7), 2242.

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Synthesis of Cholesterol-Based Polymers

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Cholesterol (degree of deacetylation ≈ 95%) was sourced from Aladdin Biochemical Technology Co., Ltd. (Shanghai, China). Undecylenic acid, chloroplatinic acid (H₂PtCl₆·6H₂O), and polymethylhydrogensiloxane (PMHS) were obtained from Shanghai Macklin Biochemical Co. (Shanghai, China). Cetyltrimethylammonium bromide (CTAB), tetraethoxysilane (TEOS), azobisisobutyronitrile (AIBN), methyl acetoacetate (MAA), ethylene dimethacrylate (EDMA), and all other analytical reagents used in the experiments were procured from Tianjin Damao Chemical Reagent Factory.

Li X., Wan L., Zhu T., Li R., Zhang M, & Lu H. (2023). Biomimetic Liquid Crystal-Modified Mesoporous Silica−Based Composite Hydrogel for Soft Tissue Repair. Journal of Functional Biomaterials, 14(6), 316.

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Electrochemical Characterization of Neurotassels

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Impedance measurements were performed in phosphate-buffered saline (PBS; pH 7.4; HyClone Laboratories) at 1 kHz using an electrochemical workstation (Reference 3000, Gamry Instruments). Electrochemical impedance spectroscopy measurements were obtained by applying a 10-mV voltage from 10 to 100,000 Hz. A platinum rod was used as the counter electrode, and an Ag/AgCl electrode (CHI111, CH Instruments Inc.) was used as the reference electrode. The 0.3-mm-thick FPCs of the 16-channel Neurotassels were soldered to a 32-channel Omnetics connector (A79022-001, Omnetics Connector Corporation). The 0.2-mm-thick FPCs of the 61-channel Neurotassels were connected to a custom printed circuit board (PCB) through a low insertion force clip (FH23-61S-0.3SHW, Hirose). The PCB has two 32-channel A79022-001 Omnetics connectors. The 128-, 256-, 512-, and 1024-channel Neurotassels were measured in a probe station (TTP4, Lake Shore Cryotronics Inc.). Platinum was electroplated from an aqueous solution of 12 mM chloroplatinic acid (Shanghai Macklin Biochemical Co. Ltd.). The Gamry Reference 3000 electrochemical workstation was used to supply a constant potential of −0.1 V for 20 s. The Neurotassels were rinsed with deionized water after electroplating.

Guan S., Wang J., Gu X., Zhao Y., Hou R., Fan H., Zou L., Gao L., Du M., Li C, & Fang Y. (2019). Elastocapillary self-assembled neurotassels for stable neural activity recordings. Science Advances, 5(3), eaav2842.

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