Male dba 1j mice

Male C57BL/6 mice were purchased from Taconic (Rensselaer, NY). Both male and female C57BL/6J, B6.129P2-IL10^tm1Cgn/J (IL-10 KO), GFPinducible- C57BL/6-Il17a^tm1Bcgen/J, male DBA/1J mice, and NOD/ShiLtJ were purchased from Jackson Laboratories (Farmington, CT). Given the C57BL/6 known difference in Th17-inducing intestinal levels of Segmented filamentous bacteria (SFB)²² (link) we tested both Taconic and Jackson mice and they were similarly protected by the high Mg2800 diet in KSIA. Therefore, all the microbiome and FMT experiments used only Taconic mice. KBxN (KRN) TCR transgenic mice (gift from Dr. C. Benoist, Boston, MA) were bred and maintained at Mount Sinai. Mice were housed under specific pathogen-free conditions and all experiments conducted under a protocol approved by the Mount Sinai Institutional Animal Care and Use Committee (protocol number 2014-0283). Mouse experiments were planned according to the ARRIVE guidelines (www.ARRIVEguidelines.org).

Male DBA/1J mice were purchased from Jackson Laboratories (Bar Harbor, ME, USA). The mice were housed at 25 ± 2 °C with a 12 h light/dark cycle in a specific pathogen-free environment, fed standard mice chow, and given food and water ad libitum. All experiments were carried out with the approval of the King Saud University Institute's animal use and care committee (KSU-SE-21-64).

Female Lewis rats age 6–8 weeks were purchased from Charles River Labs (Portage, MI). NZB/W F1 mice were purchased from Jackson Laboratories (Bar Harbor, ME). C57/BL6 mice were purchased from Taconic Biosciences (Rensselaer, NY). Male DBA1/J mice were purchased from Jackson Laboratories (Bar Harbor, ME). Female Brown Norway rats (12 weeks old) were purchased from Charles River Labs (Wilmington, MA). Balb/CN mice were purchased from Taconic Biosciences (Rensselaer, NY). SJL/J mice were purchased from Jackson Laboratories (Bar Harbor, ME). All animals were acclimated in the facility for at least seven days prior to use with rats were housed three per cage and mice housed five per cage on a 12 ​h light dark cycle with food and water provided ad libitum. All animal studies were performed in accordance with and under protocols approved by the AbbVie Bioresearch Center Institutional Animal Care and Use Committee (IACUC) in accordance with the Principles of Laboratory Animal Care and all applicable national and local laws.