Fam cysteine irgd

Manufactured by LifeTein

FAM-cysteine-iRGD is a peptide-based compound used in various research applications. It consists of a fluorescent FAM (carboxyfluorescein) label, a cysteine residue, and the iRGD (cyclic Arg-Gly-Asp-D-Phe-Cys) peptide sequence. This compound can be utilized as a tool for labeling, tracking, or detection purposes in research studies.

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Lab products found in correlation

Lipofectamine 3000 transfection kit, by Thermo Fisher Scientific (2 mentions) Dspe peg2000, by Avanti Polar Lipids (2 mentions) Trypsin, by Merck Group (2 mentions) Dotap, by Avanti Polar Lipids (2 mentions) Cholesterol, by Avanti Polar Lipids (2 mentions) Dulbecco s modified eagle s medium dmem, by Merck Group (1 mentions) Rpmi 1640 medium, by Merck Group (1 mentions)

2 protocols using fam cysteine irgd

Chemically Modified AR-ASO Lipid Nanoparticles

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Chemically modified AR-ASO (sense strand,
5′TGATTTAATGGTTGCA3′) and Cy3-conjugated ASO
(5′GCATTCTAATAGCAGC3′) were obtained from Ionis Pharmaceuticals
(Carlsbad, CA). FAM-cysteine-iRGD was purchased from LifeTein (Somerset, NJ).
DSPE-PEG2000, DPPC, DOTAP, and cholesterol were obtained from Avanti Polar Lipid
(Alabaster, Alabama). DSPE-PEG2000-MAL was from Nanosoft Polymers
(Winston-Salem, NC). The Lipofectamine 3000 transfection kit was from Invitrogen
(Carlsbad, CA). Dulbecco’s modified Eagle’s medium (DMEM),
RPMI-1640 Medium, and trypsin were from Sigma-Aldrich (St Louis, MO). All
reagents and compounds were used without further purification or
modification.

Guan J., Guo H., Tang T., Wang Y., Wei Y., Seth P., Li Y., Dehm S.M., Ruoslahti E, & Pang H.B. (2021). iRGD-liposomes enhance tumor delivery and therapeutic efficacy of antisense oligonucleotide drugs against primary prostate cancer and bone metastasis. Advanced functional materials, 31(24), 2100478.

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Chemically Modified Antisense Oligonucleotides for Targeted Delivery

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Chemically modified AR-ASO (sense strand, 5′TGATTTAATGGTTGCA3′) and Cy3-conjugated ASO (5′GCATTCTAATAGCAGC3′) were obtained from Ionis Pharmaceuticals (Carlsbad, CA). FAM-cysteine-iRGD was purchased from LifeTein (Somerset, NJ). DSPE-PEG2000, DPPC, DOTAP, and cholesterol were obtained from Avanti Polar Lipid (Alabaster, Alabama). DSPE-PEG2000-MAL was from Nanosoft Polymers (Winston-Salem, NC). The Lipofectamine 3000 transfection kit was from Invitrogen (Carlsbad, CA). Dulbecco's modified Eagle's medium (DMEM), RPMI-1640 Medium, and trypsin were from Sigma-Aldrich (St Louis, MO). All reagents and compounds were used without further purification or modification.

Guan J., Guo H., Tang T., Wang Y., Wei Y., Seth P.P., Li Y., Dehm S.M., Ruoslahti E., & Pang H. (2021). iRGD-liposomes enhance tumor delivery and therapeutic efficacy of antisense oligonucleotide drugs against primary prostate cancer and bone metastasis.

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