Si fgf18

Manufactured by Santa Cruz Biotechnology

Si-FGF18 is a recombinant human Fibroblast Growth Factor 18 (FGF18) protein produced in insect cells. FGF18 is a member of the fibroblast growth factor family and is involved in the regulation of cell growth and differentiation.

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Lab products found in correlation

Si scramble, by Santa Cruz Biotechnology (2 mentions) Opti mem, by Thermo Fisher Scientific (2 mentions) Lipofectamine 2000, by Thermo Fisher Scientific (2 mentions) Sinrf2, by Santa Cruz Biotechnology (1 mentions)

2 protocols using si fgf18

Cellular Transfection for Hypoxia-Reoxygenation Study

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L02 cells were transfected with si-FGFR3 (Santa Cruz, sc-29314) or si-NRF2 (Santa Cruz, sc-37030) or siRNA scrambled (negative) control (si-scramble; Santa Cruz, sc-37007) by using Lipofectamine 2000 for 6 h in Opti-MEM. HepG2 cells were transfected with si-USP16 (Limibio Co., Ltd) by using Lipofectamine 2000 for 6 h in Opti-MEM. LX-2 cells were transfected with si-FGF18 (Santa Cruz, sc-39478) by using Lipofectamine 2000 for 6 h in Opti-MEM. After transfection, L02 cells, HepG2 cells and LX-2 cells were subjected to H/R challenge. All the primers for si-RNA sequence used in this study are shown in the Supplementary Data 5.

Tong G., Chen Y., Chen X., Fan J., Zhu K., Hu Z., Li S., Zhu J., Feng J., Wu Z., Hu Z., Zhou B., Jin L., Chen H., Shen J., Cong W, & Li X. (2023). FGF18 alleviates hepatic ischemia-reperfusion injury via the USP16-mediated KEAP1/Nrf2 signaling pathway in male mice. Nature Communications, 14, 6107.

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FGF18 Regulation of HUVEC Response to LPS

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HUVECs were transfected with FGF18 small interfering RNA (si-FGF18; Santa Cruz, sc-39,478) or si RNA scrambled (negative) control (si scramble; Santa Cruz, sc-37,007) by using Lipofectamine 2000 (Thermo Fisher Scientific, 11,668,019) for 6 h in Opti-MEM (Thermo Fisher Scientific, 31985-070). After transfected with si-FGF18, HUVECs were treated with LPS in the presence or absence FGF18 for 6 h.

Hu Z., Dai J., Xu T., Chen H., Shen G., Zhou J., Ma H., Wang Y, & Jin L. (2024). FGF18 alleviates sepsis-induced acute lung injury by inhibiting the NF-κB pathway. Respiratory Research, 25, 108.

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