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Nod scid nod cg prkdcscid mice

Manufactured by Jackson ImmunoResearch

The NOD/Scid (NOD.Cg-Prkdcscid) mice are an immunodeficient mouse model with severe combined immunodeficiency (SCID) and non-obese diabetic (NOD) genetic background. These mice lack functional T and B cells, making them useful for xenograft studies and engraftment of human cells and tissues.

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2 protocols using nod scid nod cg prkdcscid mice

1

Congenic Murine Transplantation Model

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C57BL/6-CD45.2 and C57BL/6-CD45.1 (PepboyJ) mice were purchased from Japan SLC, Sankyo-Lab Service, Jackson Laboratories (000664, 002014), or bred in-house. For congenic transplantation experiments, 8–12 week-old male mice were used as donors and 8–12 week-old female mice were used as recipients. TLR2-knockout mice, TLR4-knockout mice, and NOD/Scid (NOD.Cg-Prkdcscid) mice were purchased from Jackson Laboratories (004650, 007227, 005557, and 001303, respectively). NG (NOD.Cg-Prkdcscid Il-2rγnull/SzJ) mice were purchased from In Vivo Science Inc. All mice were housed in a specific pathogen-free (SPF) condition with free access to food and water. All animal protocols were approved by the Animal Care and Use Committee of the Institute of Medical Science University of Tokyo, the Animal Care and Use Committee of RIKEN Tsukuba Branch, and/or the Administrative Panel on Laboratory Animal Care at Stanford University.
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2

Congenic Murine Transplantation Model

Check if the same lab product or an alternative is used in the 5 most similar protocols
C57BL/6-CD45.2 and C57BL/6-CD45.1 (PepboyJ) mice were purchased from Japan SLC, Sankyo-Lab Service, Jackson Laboratories (000664, 002014), or bred in-house. For congenic transplantation experiments, 8–12 week-old male mice were used as donors and 8–12 week-old female mice were used as recipients. TLR2-knockout mice, TLR4-knockout mice, and NOD/Scid (NOD.Cg-Prkdcscid) mice were purchased from Jackson Laboratories (004650, 007227, 005557, and 001303, respectively). NG (NOD.Cg-Prkdcscid Il-2rγnull/SzJ) mice were purchased from In Vivo Science Inc. All mice were housed in a specific pathogen-free (SPF) condition with free access to food and water. All animal protocols were approved by the Animal Care and Use Committee of the Institute of Medical Science University of Tokyo, the Animal Care and Use Committee of RIKEN Tsukuba Branch, and/or the Administrative Panel on Laboratory Animal Care at Stanford University.
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