Stock solutions were created of RAR inhibitor (BMS-453, Tocris (3409), 10mM in DMSO), methotrexate (MTX, Sigma, A6770, 100 mM in DMSO) and folinic acid (Sigma, F7878, 100mM in water) and were diluted as described in results section. All chemical treatments were done in 0.1% DMSO in 0.1X MBS and 0.1% DMSO was used as the control.
F7878
Manufactured by Merck Group
F7878 is a laboratory instrument designed for the analysis and measurement of various samples. It features advanced technology and precision engineering to provide accurate and reliable results. The core function of F7878 is to perform specified analytical tasks in a laboratory setting.
Automatically generated - may contain errors
Lab products found in correlation
2 protocols using f7878
1
Preparation of Stock Solutions for Experiments
2
Chemotherapy-Induced Mucositis and Diarrhea Model
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Chemotherapy regimen (FOLFOX) with 5-fluorouracil (5-FU, Sigma F6627), leucovorin (LV, Sigma F7878), and oxaliplatin (Sigma O9512) was injected intraperitoneally (i.p.) to cause mucositis and diarrhea. The drug-dosing schedule was based upon that used in previously published studies and our preliminary dose-finding experiments (El-Salhy et al., 2005 (link); Wagner et al., 2009 (link)). The 5-FU and LV were injected i.p. at a single dose (30 and 10 mg/kg, respectively) for 5 consecutive days (days 0–4). On the first day (day 0), the experimental animals also received oxaliplatin (1 mg/kg, i.p.) 1 h after 5-FU/LV administration. Saline was injected i.p. in control groups.
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