Data were described as median and 25–75 % interquartile range (IQR). Metric variables were compared using Mann–Whitney U test and dichotomous variables were compared using Chi-square analysis. Correlation analysis was performed using Spearman’s correlation. Cox regression proportional hazard analysis was performed to assess predictors of 28-day mortality. A forward stepwise procedure was used to identify most potent predictors.
The overall diagnostic test accuracy of ICG-PDR, SOFA, arterial serum lactate, AST levels and INR was assessed by receiver operating characteristics (ROC) expressed as their area under the curve (AUROC). We compared AUROCs at several time points using standard non-parametric methods. Estimates of diagnostic test accuracy (sensitivity, specificity) were calculated using standard methods. One-way repeated/multiple measured analysis of variance (ANOVA) was performed in patients with HH surviving until day 5. A Greenhouse-Geisser correction was used for sphericity. For data management and analyses, we used MS Excel 2008 for Mac,
SPSS 21 for Mac (SPSS, Inc. Chicago, IL, USA), and
Stata 12 for Mac (Stata Corp., College Station, TX, USA). All
p values reported are two sided and
p < 0.05 was considered significant.
Horvatits T., Kneidinger N., Drolz A., Roedl K., Rutter K., Kluge S., Trauner M, & Fuhrmann V. (2015). Prognostic impact of ICG-PDR in patients with hypoxic hepatitis. Annals of Intensive Care, 5, 47.