Adult male and female mice were used at 8–12 weeks of age. C57BL/6J (B6), B6.tiger (IL-10 GFP reporter), B6.Il10−/−, B6.Ptprca (CD45.1), B6.Il18r−/−, B6.Il18−/−, B6.Nlrp3−/−, and B6.Batf3−/− mice were purchased from The Jackson Laboratory. Mice were maintained in the University of Colorado Office of Laboratory Animal Resources.
B6 nlrp3
Manufactured by Jackson ImmunoResearch
B6.Nlrp3−/− is a genetically modified mouse model where the Nlrp3 gene has been knocked out. Nlrp3 is a component of the NLRP3 inflammasome, a protein complex involved in the inflammatory response. This model can be used to study the role of the NLRP3 inflammasome in various biological processes.
Automatically generated - may contain errors
2 protocols using b6 nlrp3
1
Mice Strains for Immunological Studies
2
Mice Strains for Immunological Studies
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