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Glacial acetic acid

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Sourced in Belgium

Glacial acetic acid is a clear, colorless liquid with a pungent odor. It has a high concentration of acetic acid, typically around 99.7%. Glacial acetic acid is widely used as a chemical reagent in various industrial and laboratory applications.

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Lab products found in correlation

Sodium hydroxide (naoh), by Merck Group (3 mentions) Hydrochloric acid (hcl), by Thermo Fisher Scientific (2 mentions) Sodium chloride (nacl), by Chem-Lab (2 mentions) Indomethacin, by Thermo Fisher Scientific (1 mentions) Sodium lauryl sulfate, by Merck Group (1 mentions) Tert butanol, by Thermo Fisher Scientific (1 mentions) Nitric acid, by Merck Group (1 mentions) Urea, by Merck Group (1 mentions) Dichloromethane dcm, by Thermo Fisher Scientific (1 mentions) Acetonitrile acn, by Thermo Fisher Scientific (1 mentions) Iron trichloride, by Merck Group (1 mentions) Acetonitrile, by Honeywell (1 mentions) Polyethylene glycol 4000, by Merck Group (1 mentions) Vanillin, by Merck Group (1 mentions) Diphenylboric acid β ethylamino ester, by Merck Group (1 mentions) Cellulose tlc plates, by Merck Group (1 mentions) Fast blue b salt, by Merck Group (1 mentions) Folin ciocalteu reagent, by Merck Group (1 mentions) Perchloric acid, by Merck Group (1 mentions) Protocatechuic acid, by Merck Group (1 mentions)

Spelling variants of this product

Acetic acid (11 citations)

4 protocols using glacial acetic acid

1

Birch Cellulose Extraction and Modification

Cited 1 time
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Dissolving pulp from birch wood, obtained from Stora Enso (Helsinki, Finland), was used as a cellulose source and pretreated as described earlier [26 (link)]. Sodium hydroxide (97%) was purchased from MilliporeSigma™ (Darmstadt, Germany). Glacial acetic acid (99%) and NaCl (99.8%) were purchased from CHEM-LAB. HCl was purchased from Fisher Scientific U.K. Limited (Loughborough, UK), and fenofibrate was purchased from Hangzhou Apichem Technology CO LTD (Hangzhou, China). TEMPO (98%), indomethacin, HNO3 (37%), and tert-butanol (99%) were obtained from ThermoFisher (Kandel, Germany). Sodium lauryl sulfate (SLS) was obtained from Merck KGaA (Darmstadt, Germany). Urea (99.5%), sodium acetate acid (99%+), NaClO (10–15%), NaClO2 (80%), acetone (99%), methyl sulfoxide (DMSO, 99.9%), acetonitrile (ACN, 99%), and dichloromethane (DCM, 99.9%) were purchased from ACROS Belgium (Geel, Belgium).
Xie F., De Wever P., Fardim P, & Van den Mooter G. (2021). TEMPO-Oxidized Cellulose Beads as Potential pH-Responsive Carriers for Site-Specific Drug Delivery in the Gastrointestinal Tract. Molecules, 26(4), 1030.
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2

Cellulose Extraction from Birch Wood

Cited 1 time
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Dissolving pulp from birch wood, obtained from Stora Enso (Helsinki, Finland), was used as a cellulose source, and pretreated as described earlier (De Wever et al., 2021 (link)). Sodium hydroxide (97%), urea (≥99.5%), nitric acid (69%), sodium meta-periodate (≥99.0%), and Polysorbate 80 were purchased from Millipore Sigma™ (Darmstadt, Germany). Glacial acetic acid (99%), and NaCl (99.8%) were purchased from CHEM-LAB (Zedelgem, Belgium). Ethylenediamine monohydrate (for synthesis) was purchased from Sigma-Aldrich (Darmstadt, Germany). Hydrochloric acid (36%) was purchased from Fisher Scientific U.K. Limited (Loughborough, UK). Indomethacin (IND), Tert-butanol (TBA,99%) was obtained from ThermoFisher. Fenofibrate (FNB) was purchased from Hangzhou Apichem Technology CO LTD (Hangzhou, China). Itraconazole (ITZ) was procured from Neuland Laboratories Ltd. (Jinnaram, India). Dichloromethane (DCM) and acetonitrile (ACN) were purchased from Fisher Scientific (Loughborough, UK). Methanol (MeOH), Ethanol (EtOH), Dimethyl sulfoxide (DMSO,99.9%) and Ethylene glycol (99.8%) were bought from ACROS Belgium (Geel, Belgium). All solvents were of analytical grade and all materials were used as received.
Xie F., Slak J., Fardim P, & Van den Mooter G. (2022). Novel cationic cellulose beads for oral delivery of poorly water-soluble drugs. International Journal of Pharmaceutics: X, 5, 100146.
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3

Phytochemical Characterization and Antioxidant Assays

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Acetic anhydride, bismuth nitrate, and sodium nitrite were obtained from Panreac® (Barcelona, Spain). Diphenylboric acid-β-ethylamino ester, fast blue B salt, gallic acid, iodine, oleanolic acid, polyethylene glycol-4000, protocatechuic acid, and vanillin were obtained from Sigma-Aldrich® (Steinheim, Germany). Ethanol was obtained from Aga® (Prior Velho, Portugal). Glacial acetic acid and sulfuric acid were obtained from Chem-Lab® (Zedelgem, Belgium). Acetone, Folin–Ciocalteu reagent, hydrochloric acid 37% extra pure, iron trichloride, perchloric acid, potassium iodate GR, sodium carbonate, sodium hydroxide, and TLC cellulose plates (catalog number 105552) were obtained from Merck® (Darmstadt, Germany). Butanol-1 and methanol were obtained from Fisher Chemicals® (Leicestershire, UK). Ferrous sulfate was obtained from May and Baker LTD® (Dagenham, UK). The (+)-Catechin (hydrate) was obtained from Cayman Chemical Company® (Ann Arbor, MI, USA). Aluminum chloride was obtained from Fluka® (Buchs, Switzerland). Acetonitrile was obtained from Honeywell Riedel-de Haën™ (Seelze, Germany). Formic acid 99–100% was obtained from VWR Chemicals (Fontenay-sous-Bois, France). All used reagents were of analytical grade.
Encarnação S., Serrano R., Almeida C, & Silva O. (2022). Micromorphology and Chemical Studies on Anacardium occidentale L. Stem Bark as an Herbal Medicine. Plants, 12(1), 7.
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4

Quantitative Analysis of Tacrolimus

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Tacrolimus was procured from Lucerna Chem AG (Lucerne, Switzerland) and the used Prograf® capsule formulation was manufactured by Astellas (Tokyo, Japan). Fasted and fed state simulated intestinal fluid (3F powder) powder was bought from Biorelevant (London, UK). The solvents methanol, acetonitrile, and formic acid (99%) were purchased from Biosolve (Valkenswaard, The Netherlands). Purified water was produced using a Purelab® Flex water system from Veolia (Paris, France). Sodium acetate was obtained from VWR chemicals (Radnor, PA, USA) and glacial acetic acid from Chem-Lab (Zedelgem, Belgium). Both products were used to make the acetate buffer at pH 4.5 according to the United States Pharmacopoeia (USP).
Van der Veken M., Brouwers J., Ozbey A.C., Umehara K., Stillhart C., Knops N., Augustijns P, & Parrott N.J. (2023). Investigating Tacrolimus Disposition in Paediatric Patients with a Physiologically Based Pharmacokinetic Model Incorporating CYP3A4 Ontogeny, Mechanistic Absorption and Red Blood Cell Binding. Pharmaceutics, 15(9), 2231.
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