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750 scanner

Manufactured by GE Healthcare

The 750 scanner is a medical imaging device manufactured by GE Healthcare. It is a diagnostic tool designed to capture high-quality images for medical professionals to analyze. The core function of the 750 scanner is to provide detailed imaging of the body's internal structures, enabling healthcare providers to make informed decisions about patient care.

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10 protocols using 750 scanner

1

Resting-State fMRI Acquisition Protocol

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Functional and anatomical MRI data were acquired on a 3 T GE 750 scanner. Structural T1 images were collected with an 8-channel head coil using a 3D FSPGR sequence (flip angle = 11, TE = 2.6 ms, TR = 6.4 ms, 180 slices, 1 mm isotropic resolution). Two runs of resting state data were acquired with a 32-channel head coil using an echo planar imaging (EPI) sequence (flip angle = 77, TE = 30 ms, TR = 2000 ms, 34 slices, 3.5 mm isotropic resolution, 140 acquisition frames per run, 4 minutes and 40 seconds long). During the two resting state runs, participants were instructed to rest quietly with their eyes open without falling asleep. The examiner monitored that participants kept their eyes open and stayed awake during these scans using an in-scanner eye-tracking camera.
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2

Multi-shell DWI Acquisition Protocol

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A multi-shell spin-echo, echo-planar imaging sequence was used to collect DWI data using a Nova 32 channel head coil and a 3 Tesla GE 750 scanner. Three shells of different encoding strengths (b-values of 500, 800 and 2000 s/mm2) were acquired with 9, 18 and 36 directions, respectively. There were six reference scans without any diffusion encoding (b=0 s/mm2). Other parameters included: repetition time (TR) = 7000 ms; echo time (TE) = 91 ms; field of view (FOV) = 256 mm; 75 slices and 2x2x2 mm3 voxel resolution.
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3

Multimodal Acquisition of Simon Task Data

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Data were acquired on a 3T GE 750 scanner with a 32-channel head coil. Two structural T1 images were collected for each participant using a 3D-FSPGR sequence (flip angle=11, TE=2.588ms, TR=6.412ms, 180 slices, 1mm isotropic resolution). Three runs of Simon task data were acquired with an echo planar imaging sequence (flip angle=77, TE=25ms, TR=2000ms, 44 slices, 3.0mm isotropic resolution, 160 acquisition frames, 5 minutes and 32 seconds long). Structural data were processed using standard FreeSurfer v6.0 pipeline (recon-all)40 (link),41 (link) and functional data using Statistical Parametric Mapping (SPM)12, AFNI, and FSL (Supplement).
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4

Whole-Brain Neuroimaging of Threat Extinction Recall

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Whole-brain neuroimaging data were collected using a 3 T General Electric 750 scanner and 32-channel head coil. For the nonsocial threat extinction recall task, 343 functional image volumes were collected during 2 runs of 23 min 9 s each. For the social threat extinction recall task, 272 functional image volumes were collected during 3 runs of 10 min 26 s each. For both social and nonsocial threat extinction recall tasks, functional image volumes with 47 contiguous interleaved axial slices (in-plane resolution 2.5 mm, 3 mm slice thickness) were obtained with a T2*-weighted echo-planar sequence (TR = 2300 ms; TE = 25 ms; flip angle = 50; field of view [FOV] = 240 mm; matrix =96×96 ). All functional data were anatomically localized and coregistered to a high-resolution T1-weighted volumetric scan of the whole brain, using a magnetization prepared gradient echo sequence (MPRAGE; TE = min full; TI = 425 ms; flip angle = 7; FOV = 256 mm; matrix = 256 × 256 ; in plane resolution 1.0 mm).
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5

Structural MRI of Amygdala and Hippocampus

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Neuroimaging data were collected using a 3T GE 750 scanner with a 32-channel head coil at one timepoint between child age 7 and 9 years. Two structural T1 images were collected per participant using a 3D FSPGR sequence (11° flip angle, TE = 2.588 ms, TR = 6.412 ms, 180 slices, 1 mm isotropic resolution). Structural images were visually inspected, and subjects with apparent motion artifacts were excluded. T1 images were anatomically segmented using the recon-all command in FreeSurfer v6.0, segmentations were visually inspected by a trained research assistant for quality assurance, and amygdala and hippocampal volumes were extracted (Fischl et al., 2002 (link), 2004 (link)).
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6

Multimodal Neuroimaging Acquisition Protocol

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Functional and anatomical images were collected on a 3T GE 750 scanner. Structural T1 images were collected with an eight-channel head coil using a three-dimensional (3D) FSPGR sequences (flip angle = 11, TE = 2.588 ms, TR = 6.412 ms, 180 slices, 1 mm × 1 mm × 1 mm resolution). Two runs of resting state data were acquired with a 32-channel head coil using an echo planar imaging (EPI) sequence (flip angle = 77, TE = 30 ms, TR = 2,000 ms, 34 slices, 3.5 mm × 3.5 mm × 3.5 mm resolution, 140 acquisition frames, 4 min and 40 s long).
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7

fMRI Protocol for MDMT Task

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Participants were scanned in a 3T GE 750 scanner using an 8-channel head array coil. Each scanning session included a three-plane scout scan, a sagittally acquired spoiled gradient recalled (SPGR) sequence for acquiring T1-weighted images (FOV 256 cm; matrix: acquired 192 × 256 matrix resampled to 256 × 256; 172 slices; thickness: 1 mm; TR = 8 ms, TE: 3 ms, flip angle: 12 degrees, inversion time = 450 ms) and one T2*-weighted axially acquired echo-planar imaging (EPI) scans to measure blood oxygen level dependent (BOLD) signals (parameters: 3.75 mm × 3.75 mm × 3 mm; 64 × 64 acquisition matrix with a 1mm gap, TR = 1.5 s, TE = 32 ms, flip angle of = 80 degrees and 30 slices (whole brain)). The MDMT trial length was determined by the pace of the each subject’s responses therefore the average length of acquisition ranged from 166 to 279 reps (M = 218 reps).
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8

Multimodal neuroimaging of resting-state brain

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Functional and anatomical images were acquired on a 3T GE 750 scanner with a 32-channel head coil. Two structural T1 images were collected for each participant with an 8-channel head coil using a 3D FSPGR sequence (flip angle=11, TE=2.588ms, TR=6.412ms, 180 slices, 1mm isotropic resolution). Two runs of resting-state data were acquired using an echo planar imaging (EPI) sequence (flip angle=77, TE=30ms, TR=2000ms, 34 slices, 3.5mm isotropic resolution, 140 acquisition frames, 4 minutes and 40 seconds long). During the two resting-state runs, participants were instructed to rest quietly with their eyes open without falling asleep. The examiner monitored that participants kept their eyes open and stayed awake during these scans using an in-scanner eye-tracking camera.
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9

Chloral Hydrate Induced Sleep MRI

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Before MRI scanning, all of the participants were administered 0.5% chloral hydrate 0.5 ml/kg (maximum dose 10 ml) orally to induce and maintain sleep. All participants continued sleeping during scanning and were not stimulated.
Most of structural MRI data (n = 35) were collected on a 3.0T SEMENS Skyra scanner at the Foshan Chancheng Hospital, Foshan, China using a T1-weighted MPRAGE sequence (TE = 2.98 ms, TR = 2,300 ms, resolution = 1.0 mm × 1.0 mm × 1.0 mm, space gap = 0 mm, flip angle = 9°, 144 slices). The remaining MRI data (n = 9) were collected on a 3.0T GE 750 scanner using a T1-weighted MPRAGE sequence (TE = 3.2 ms, TR = 8.4 ms, FOV = 256 mm, Matrix = 256 × 256 mm, resolution = 1.0 mm × 1.0 mm × 1.0 mm, space gap = 0 mm, flip angle = 15°, 146 slices). The scanner information was coded as 1 and 2 and added as a categorical variable in the statistical analyses.
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10

Structural and Functional MRI of Simon Task

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Data were acquired on a 3T GE 750 scanner with a 32-channel head coil. Two structural T1 images were collected for each participant using a 3D-FSPGR sequence (flip angle = 11, TE = 2.588 ms, TR = 6.412 ms, 180 slices, 1 mm isotropic resolution). Three runs of Simon task data were acquired with an echo planar imaging sequence (flip angle = 77, TE = 25 ms, TR = 2000 ms, 44 slices, 3.0 mm isotropic resolution, 160 acquisition frames, 5 min and 32 s long).
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