Vorapaxar

Manufactured by Selleck Chemicals

Sourced in Germany

Vorapaxar is a laboratory equipment product manufactured by Selleck Chemicals. It functions as a thrombin receptor antagonist.

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Lab products found in correlation

Platelet activating factor 16 paf, by Merck Group (2 mentions) 9 11 dideoxy 11α 9α epoxymethanoprostaglandin f 2α u 46619, by Merck Group (2 mentions) Sodium chloride saline, by B. Braun (2 mentions) Ticagrelor, by Merck Group (2 mentions) Drospirenone, by Selleck Chemicals (1 mentions) Ciclesonide, by Selleck Chemicals (1 mentions) Atp a1852, by Merck Group (1 mentions) Pam3csk4 tlrl pms, by InvivoGen (1 mentions) Dimethyl sulfoxide (dmso), by Merck Group (1 mentions) Acetylsalicylic acid, by Merck Group (1 mentions) Phosphate buffer, by Merck Group (1 mentions) Dimethyl sulphoxide dmso, by Merck Group (1 mentions) Arachidonic acid, by Roche (1 mentions)

3 protocols using vorapaxar

Pharmacological Agents in Cellular Assays

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LPS (L-3129), Nigericin (N-7143) and ATP (A1852) were purchased from Sigma–Aldrich. Poly(dA:dt) (tlrl-patn), Flagellin (tlrl-stfla) and Pam3CSK4 (tlrl-pms) were purchased from Invivogen. MPTP (S4732), dihydroergotamine mesylate (S5751), fluocinolone acetonide (S2470), azilsartan medoxomil (S3057), vorapaxar (S8067), astemizole (S0398), eplerenone (S1707), drospirenone (S1377), ciclesonide (S4646) and talniflumate (S6439) were purchased from Selleck.

Liu Y., Liu T., Zhou Y., Li W., Wang M., Song N., Zhang W., Jiang J., Yuan S., Ding J., Hu G, & Lu M. (2022). Impeding the combination of astrocytic ASCT2 and NLRP3 by talniflumate alleviates neuroinflammation in experimental models of Parkinson's disease. Acta Pharmaceutica Sinica. B, 13(2), 662-677.

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Platelet Aggregation Inhibitor Characterization

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Dimethyl sulfoxide (DMSO); acetylsalicylic acid (ASA); ticagrelor; ristomycin monosulfate (ristocetin); platelet activating factor-16 (PAF) and 9,11-dideoxy-11α,9α-epoxymethanoprostaglandin F 2α (U-46619) were purchased from Sigma (St. Louis, MO, USA). Thrombin receptor agonist peptide-6 (TRAP), adenosine-5-diphosphate (ADP) and AA were purchased from Roche (Basel, Switzerland). Vorapaxar was purchased from Selleck Chemicals GmbH (Planegg, Germany). Collagen was purchased from Diagnostica, a.s. (Prague, Czechia) and 0.9% sodium chloride (saline) from B. Braun (Melsungen, Germany).

Konečný L., Hrubša M., Karlíčková J., Carazo A., Javorská L., Matoušová K., Krčmová L.K., Blaha V., Bláha M, & Mladěnka P. (2023). The Impact of Convertase Subtilisin/Kexin Type 9 Monoclonal Antibodies with and without Apheresis on Platelet Aggregation in Familial Hypercholesterolemia. Cardiovascular drugs and therapy.

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Platelet Aggregation Reagent Protocol

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Phosphate buffer, dimethyl sulphoxide (DMSO), ASA, ticagrelor, ristomycin monosulphate (ristocetin), platelet-activating factor-16 (PAF) and 9,11-dideoxy-11α,9α-epoxymethanoprostaglandin F_2α (U-46619) were purchased from Sigma-Aldrich (St. Louis, MO, USA). Thrombin receptor agonist peptide-6 (TRAP), adenosine-5-diphosphate (ADP) and arachidonic acid (AA) were purchased from Roche (Basel, Switzerland). Vorapaxar was purchased from Selleck Chemicals GmbH (Planegg, Germany). Collagen was purchased from Diagnostica, a.s. (Prague, Czechia) while 0.9% sodium chloride (saline) was purchased from B. Braun (Melsungen, Germany).

Konečný L., Hrubša M., Karlíčková J., Carazo A., Javorská L., Matoušová K., Krčmová L.K., Šmahelová A., Blaha V., Bláha M, & Mladěnka P. (2023). The Effect of 4-Methylcatechol on Platelets in Familial Hypercholesterolemic Patients Treated with Lipid Apheresis and/or Proprotein Convertase Subtilisin Kexin 9 Monoclonal Antibodies. Nutrients, 15(8), 1842.

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