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Stata statistical software version 12

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Stata is a general-purpose statistical software package developed by StataCorp. Version 12.0 provides a comprehensive set of tools for data manipulation, analysis, and visualization. The software supports a wide range of statistical methods, including regression analysis, time series analysis, and survey data analysis.

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140 protocols using stata statistical software version 12

1

Preeclampsia Risk Factors: Allostatic Load and Obesity

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We used conditional logistic regression to compare demographic variables, biomarker values, and allostatic load comparisons between the preeclamptic cases and matched control groups. Significance was considered as p<0.05. In considering covariates, we included demographic components into the model that demonstrated a univariate relationship to the outcome with p<0.05.
We did exploratory analyses to evaluate the model. We used conditional logistic regression in univariate analyses of the cardiovascular, metabolic, and inflammatory domains of allostatic load. Because obesity is a well-established risk factor for preeclampsia, we compared the a priori model of allostatic load to that of obesity. We used Akaike information criterion (AIC) to compare the allostatic load model to a model including only obesity. For comparing AIC of the models, we considered a difference in the values of at least 1-2 between the models as a difference in the goodness-of-fit with the lower AIC model being the better-fit model for the outcome preeclampsia.(14 ) We also determined AIC for the domains and any significant individual components for the comparison to the allostatic load model. All statistical analyses were conducted using Stata Statistical Software, Version 12 (Stata Statistical Software: Release 12, College Station, TX: StataCorp LP).
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2

COVID-19 Mortality Comorbidities in Brazil

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Data were extracted from the bulletin on the epidemiological situation of COVID-19, made available by each of the 26 Brazilian States and the Federal District, on their official websites. The obtained data were evaluated according to the following variables: confirmed cases, ICU hospitalizations and deaths. The epidemiological and clinical profiles of the death’s cases were also described, considering sex, age, and the presence and type of comorbidities, respectively.
Because not all States reported the presence of comorbidities in fatal cases, the random-effects model to estimate the pooled prevalence of comorbidities in deaths and their respective confidence intervals (CI) of 95%, was used. The heterogeneity of prevalence was analyzed by State using the Higgins test (I2), which presents the percentage of variation across them. These analyses were performed using the Stata statistical software, version 12 (Stata Corp LLC, Texas, USA).
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3

Evaluating Patient-Reported Outcome Measures

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First, the items s25, s27, s45, s46, s49, s66, s67, and s68 were recoded so that higher values indicate more problems, to ensure comparability with the other items.
We then calculated the range and mean of each item together with the percentage of responses in each response category. In a next step, we defined for each item the percentage of patients who completed it, who found it irritating, or difficult to understand.
We hypothesised what items could be combined into a scale and calculated Cronbach’s alpha to define its preliminary internal consistency.
All analyses were performed using STATA statistical software, version 12 (StataCorp, TX, USA).
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4

Longitudinal Analysis of Heart Rate Variability

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The questions and hypotheses of the current study were examined via descriptive and inferential statistics. The quantitative variables and qualitative variables were described using the mean (SD) and numbers (%), respectively. In addition, comparisons between HRV indices before and after the study were performed using the paired t-test. A generalized estimating equation (GEE) was used for multivariate data analysis after the effects of the variables of gender, age, and the body mass index (BMI) were eliminated. This model is commonly considered to analyze longitudinal/clustered data.
A p value < 0.05 was considered statistically significant. The statistical analyses were performed using SPSS Statistics, version 22.0, and STATA Statistical Software, version 12.
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5

Assessing Premature Mortality Risk in TBI

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We estimated the risk of premature death after having been diagnosed as having TBI with matched or sibling controls24 (link),35 (link) using the clogit command in Stata statistical software, version 12 (StataCorp). The clogit command fits conditional (fixed-effects) logistic regression models to matched case-control groups. Traumatic brain injury patients and controls were followed up from the same time point (ie, from 6 months after TBI). We included 3 confounders (low income, single marital status, and immigrant status) on theoretical grounds based on related work on other neuropsychiatric disorders35 (link),36 (link) and tested whether they were each associated (at P < .05) with caseness and outcome measures, respectively.37 (link) Separately, we adjusted for emigration rates after TBI. In sensitivity analyses, we stratified by sex, psychiatric comorbidity (lifetime and separately for preexisting and new diagnoses), and co-occurring injuries at the time of TBI (Author Table 1). The STROBE (Strengthening the Reporting of Observational Studies in Epidemiology) guidelines were followed (Author Table 2).
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6

Longitudinal Comparison of Intervention Outcomes

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As over 90% of the sample attended all assessments, an intention to treat complete case analysis was conducted. Comparisons were made between the two groups for data that related to the 12-month period starting at the date that the first assessment was completed.
Between group comparisons were carried out in primary and secondary outcome measures for the differences between baseline values and values at three months and 12 months and baseline by t-tests for unadjusted analysis and linear regression models for analysis adjusted for age.
An ancillary analysis was conducted to examine the change in primary and secondary outcome measures over time. Multilevel regression modelling was used, with fixed effects for intervention, time and treatment x time, and random effects for the intercepts at each time point. The analyses were conducted using the STATA statistical software version 12 [28 ].
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7

Randomized Controlled Trial of Park Prescription

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Participants were randomized into one of the two groups based on computer-generated random numbers using Stata statistical software version 12 [31 ]. Block sizes were generated randomly using a minimum block size of four and a maximum block size of ten. The group assignments were handed to a separate study team member to be placed into sequentially-numbered opaque envelopes and sealed. The envelopes had the participant ID documented on the outside according to the randomization lists and a slip of paper stating ‘intervention’ or ‘control’ was placed in each envelope. The envelopes were opened by the study team member who would perform the park prescription counselling component of the intervention after confirmation of eligibility, provision of informed consent and completion of the baseline assessment in the presence of the study participants, which ensured allocation concealment. Due to the nature of the intervention and the logistics of the study, participants and research staff were subsequently not blinded to the group allocation.
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8

Logistic Regression Analysis of Screening Performance

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We conducted logistic regression models overall and by patient subgroups while controlling for age, exam year, race/ethnicity, timing of last screen and indicator variables for screening facility. For specificity, we also used generalized estimating equations to account for clustering of exams by patient. Model-based standardization (predictive margins) was then used to estimate the overall and stratum-specific performance characteristics [5 (link),6 (link)]. Ninety-five percent confidence intervals were estimated using the delta method as implemented in the margins command within Stata. All analyses were conducted using Stata statistical software, version 12 (Stata Corp, College Station, TX). All p-values are two-sided.
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9

Longitudinal Outcomes of Detained Youth

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All analyses were conducted using STATA statistical software, version 12 (StataCorp) with its survey routines. To generate prevalence estimates and inferential statistics that reflect CCJTDC’s population, each participant was assigned a sampling weight augmented with a nonresponse adjustment to account for missing data. Because minorities are disproportionately incarcerated, weighted estimates for males and females overall are similar to those for African American males and females.
We present prevalence estimates for participants who were still living at follow-up. (Five and 12 years after detention, 50 and 97 participants had died, respectively.) Because incarceration prevents people from achieving many positive outcomes, we also present prevalence only for participants living in the community during the recall period (see eMethods). We used logistic regression to examine sex and racial/ethnic differences in outcomes, adjusting for age at detention and legal status. We used the Latent Class Analysis Stata plugin24 to empirically identify “classes” of participants who exhibited similar patterns of positive outcomes 12 years after detention. Three participants who self-identified as “other” race/ethnicity were excluded from all analyses. We conducted separate analyses for males and females because combining them could obfuscate important differences.
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10

Costing Accuracy Improvement Evaluation

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Descriptive statistics were used to describe the demographic details of the episodes of care included in the audit and in the total sample. A paired t-test was used to determine the effect of the revised linking rules and costing process on the accuracy of the costing data, as measured by the number of activities costed, the accuracy of activities costed and the number of activities missing from the costing.
The threshold for statistical significance was set at P = 0.05. Statistical analysis was performed using Stata statistical software Version 12 (StataCorp).
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