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Brca2 sirna

Manufactured by Horizon Discovery
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BRCA2 siRNA is a type of small interfering RNA (siRNA) designed to target and silence the expression of the BRCA2 gene. The BRCA2 gene plays a crucial role in DNA repair, and its silencing can be used for research purposes related to cancer biology and therapeutic development.

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Lab products found in correlation

Control sirna, by Eurofins (2 mentions) Blm sirna, by Eurofins (2 mentions) Recq5 sirna, by Eurofins (2 mentions) Trex1 sirna, by Eurofins (2 mentions) Ctip sirna, by Eurofins (2 mentions) Gen1 sirna, by Eurofins (2 mentions) Mus81 sirna, by Horizon Discovery (2 mentions) Slx1 sirna, by Horizon Discovery (2 mentions) Ercc1 sirna, by Horizon Discovery (2 mentions) Mre11 sirna, by Horizon Discovery (2 mentions) Exo1 sirna, by Horizon Discovery (2 mentions) Dna2 sirna, by Horizon Discovery (2 mentions) Recq1 sirna, by Horizon Discovery (2 mentions) Recq4 sirna, by Horizon Discovery (2 mentions) Wrn sirna, by Horizon Discovery (2 mentions) Rad51 sirna, by Horizon Discovery (2 mentions) Lipofectamine rnaimax, by Thermo Fisher Scientific (2 mentions)

Close spelling variants of this product

BRCA2 SiRNAs

2 protocols using brca2 sirna

1

Silencing DNA repair genes in cells

Cited 3 times
Check if the same lab product or an alternative is used in the 5 most similar protocols
The control siRNA (5’-UAAUGUAUUGGAACGCAUA-3’), BLM siRNA (5’-CCGAAUCUCAAUGUACAUAGA-3’)65 (link), RECQ5 siRNA (5’-CAGGAGGCUGAUAAAGGGUUA-3’)65 (link), TREX1 siRNA (5’-CCAAGACCAUCUGCUGUCA-3’)66 (link), CTIP siRNA (5’-GCUAAAACAGGAACGAAUC-3’)67 (link), GEN1 siRNA (5’-GUAAAGACCUGCAAUGUUA-3’) were purchased from Eurofins. The MUS81 siRNA (5’-CAGCCCUGGUGGAUCGAUA-3’ and 5’-CAUUAAGUGUGGGCGUCUA-3’)68 (link), SLX1 siRNA (5’-UGGACAGACCUGCUGGAGAUU-3’)69 (link), ERCC1 siRNA (SMARTpool ON-TARGET plus L-006311), MRE11 siRNA (SMARTpool ON-TARGET plus L-009271), EXO1 siRNA (SMARTpool ON-TARGET plus L-013120), DNA2 siRNA (SMARTpool ON-TARGET L-026431), RECQ1 siRNA (SMARTpool ON-TARGET plus L-013597), RECQ4 siRNA (SMARTpool ON-TARGET plus L-010559), WRN siRNA (SMARTpool ON-TARGET plus L-010378), BRCA2 siRNA (SMARTpool ON-TARGET plus L-003462) and RAD51 siRNA (SMARTpool ON-TARGET plus L-003530) were purchased from Dharmacon. Cells were seeded one day before siRNA treatment and transfected with 25 nM of siRNA using Lipofectamine RNAiMAX (Life Technologies).
Chan Y.W., Fugger K, & West S.C. (2017). Unresolved recombination intermediates lead to ultra-fine anaphase bridges, chromosome breaks and aberrations. Nature cell biology, 20(1), 92-103.
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2

Silencing DNA repair genes in cells

Cited 3 times
Check if the same lab product or an alternative is used in the 5 most similar protocols
The control siRNA (5’-UAAUGUAUUGGAACGCAUA-3’), BLM siRNA (5’-CCGAAUCUCAAUGUACAUAGA-3’)65 (link), RECQ5 siRNA (5’-CAGGAGGCUGAUAAAGGGUUA-3’)65 (link), TREX1 siRNA (5’-CCAAGACCAUCUGCUGUCA-3’)66 (link), CTIP siRNA (5’-GCUAAAACAGGAACGAAUC-3’)67 (link), GEN1 siRNA (5’-GUAAAGACCUGCAAUGUUA-3’) were purchased from Eurofins. The MUS81 siRNA (5’-CAGCCCUGGUGGAUCGAUA-3’ and 5’-CAUUAAGUGUGGGCGUCUA-3’)68 (link), SLX1 siRNA (5’-UGGACAGACCUGCUGGAGAUU-3’)69 (link), ERCC1 siRNA (SMARTpool ON-TARGET plus L-006311), MRE11 siRNA (SMARTpool ON-TARGET plus L-009271), EXO1 siRNA (SMARTpool ON-TARGET plus L-013120), DNA2 siRNA (SMARTpool ON-TARGET L-026431), RECQ1 siRNA (SMARTpool ON-TARGET plus L-013597), RECQ4 siRNA (SMARTpool ON-TARGET plus L-010559), WRN siRNA (SMARTpool ON-TARGET plus L-010378), BRCA2 siRNA (SMARTpool ON-TARGET plus L-003462) and RAD51 siRNA (SMARTpool ON-TARGET plus L-003530) were purchased from Dharmacon. Cells were seeded one day before siRNA treatment and transfected with 25 nM of siRNA using Lipofectamine RNAiMAX (Life Technologies).
Chan Y.W., Fugger K, & West S.C. (2017). Unresolved recombination intermediates lead to ultra-fine anaphase bridges, chromosome breaks and aberrations. Nature cell biology, 20(1), 92-103.
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