Eudragit rs30d

Manufactured by Evonik

Sourced in Germany

Eudragit® RS30D is a water-based acrylic resin dispersion. It is used in the pharmaceutical industry as a coating material for the production of pharmaceutical dosage forms.

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5 protocols using eudragit rs30d

Comprehensive Characterization of Anticancer Compounds

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Almost all reagents were acquired from Sigma-Aldrich (Steinheim, Germany) and Sigma Chemical Co. (St. Louis, MO, USA). Eudragit RS 30 D was kindly supplied by Evonik Operations GmbH (Darmstadt, Germany). For the LC/DAD-ESI-MS analysis, the solvents employed were supplied by Merck (Darmstadt, Germany). The human tongue squamous carcinoma cell line (HSC-3) as well as the human squamous cell carcinoma (TR146) were provided from American Type Culture Collection (ATCC, Manassas, VA, USA). Cells reagents were supplied by Invitrogen Corporation (Life Technologies, S.A., Madrid, Spain).

Teixeira F., Silva A.M., Sut S., Dall’Acqua S., Delerue-Matos C., Estevinho B., Costa P.C, & Rodrigues F. (2023). Development and Characterization of Microparticles with Actinidia arguta Leaves Extract by Spray-Drying: A New Mind-Set Regarding Healthy Compounds for Oral Mucositis. Antioxidants, 12(8), 1496.

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Metformin-Alginate Nanoparticle Formulation

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Metformin (M, 98%), sodium alginate (SA, 99%), chenodeoxycholic acid (CDCA, 99%) and Poloxamer 407 were purchased from Sigma Chemical Co (St. Louis, MO, USA). Eudragit^® RS30D, RL30D and NM30D polymers were supplied by Evonik Industries (Essen, Germany). Calcium chloride dihydrate (CaCl₂ 2H₂O 98%) was obtained from Scharlab S.L (Barcelona, Spain). All reagents and solvents were HPLC grade, used without further purification or modification and were supplied by Merck (Bayswater, VIC, Australia).

Mooranian A., Carey L., Ionescu C.M., Walker D., Jones M., Wagle S.R., Kovacevic B., Foster T., Chester J., Johnston E., Mikov M, & Al-Salami H. (2021). The Effects of Accelerated Temperature-Controlled Stability Systems on the Release Profile of Primary Bile Acid-Based Delivery Microcapsules. Pharmaceutics, 13(10), 1667.

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Eudragit RS30D-based Drug Formulation

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Eudragit® RS30D (Evonik®– Germany) and triethyl citrate (TEC) (Morflex®–EUA); α-Gluco-oligosaccharide (Bioecolians®, Solabia – France) and other reagents of analytical grade were used in the study.

de Oliveira F.M., Bunhak É.J., dos Santos L.F., Barros P.D, & Cavalcanti O.A. (2019). α-Gluco-oligosaccharide in the research and development of a polymeric material for modified drug delivery. Heliyon, 5(12), e03053.

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Metronidazole Controlled-Release Formulation

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The materials used were metronidazole as a donation sample from SQUARE Pharmaceuticals Ltd., Bangladesh, Carbopol 934P (Colorcon Asia Pvt. Limited, India), Polylactic Acid (PLA) (Merck, Germany), Eudragit RS30D (Evonik, Germany), Eudragit RL30D (Evonik, Germany), light liquid paraffin, petroleum ether (Merck, Germany), sodium hydroxide (Merck, Germany), potassium dihydrogen phosphate (Merck, Germany), and distilled water.

Dewan I., Islam M.M., Al-Hasan M., Nath J., Sultana S, & Rana M.S. (2015). Surface Deposition and Coalescence and Coacervation Phase Separation Methods: In Vitro Study and Compatibility Analysis of Eudragit RS30D, Eudragit RL30D, and Carbopol-PLA Loaded Metronidazole Microspheres. Journal of Pharmaceutics, 2015, 254930.

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Diclofenac Sodium Modified-Release Capsules

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Diclofenac sodium (Amoli Organics, Mumbai, India). Inert cores: calcium phosphate-based (DCPA) pellets—PharSQ^® Spheres CM M (Chemische Fabrik Budenheim, Budenheim, Germany), microcrystalline cellulose pellets—VIVAPUR^® MCC Spheres 500 (JRS Pharma, Rosenberg, Germany), sugar spheres—pharm-a-spheres^TM MESH 35-25 (Hanns G. Werner GmbH, Tornesch, Germany), isomalt starter pellets—galenIQ^TM 960 (BENEO-Palatinit GmbH, Mannheim, Germany). Film coating systems: Vivacoat^® FM-1M 000 (JRS Pharma, Rosenberg, Germany), Aquarius^® Control ENA (Ashland, Covington, KY, USA), Eudragit^® RL30D and Eudragit^® RS30D (Evonik, Darmstadt, Germany). Transparent hard gelatin capsule shells, size “00” (Pharmapol Arzneimittelvertrieb GmbH, Dägeling, Germany). DicloDuo^® 75 mg, modified-release capsules (Pharmaswiss Česká republika s.r.o., Praha, Czech Republic).

Zakowiecki D., Frankiewicz M., Hess T., Cal K., Gajda M., Dabrowska J., Kubiak B., Paszkowska J., Wiater M., Hoc D., Garbacz G, & Haznar-Garbacz D. (2021). Development of a Biphasic-Release Multiple-Unit Pellet System with Diclofenac Sodium Using Novel Calcium Phosphate-Based Starter Pellets. Pharmaceutics, 13(6), 805.

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