Ox40l ik 1

Manufactured by BD

OX40L (IK-1) is a recombinant human OX40 ligand protein. OX40L is a member of the tumor necrosis factor (TNF) superfamily and is involved in the regulation of T-cell-mediated immune responses.

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Lab products found in correlation

Poly 1 c, by InvivoGen (1 mentions) Recombinant human tslp, by R&D Systems (1 mentions) Cd141 ad5 14h12, by Miltenyi Biotec (1 mentions) Ionomycin, by Merck Group (1 mentions) Phorbol myristate acetate (pma), by Merck Group (1 mentions) Curdlan, by Merck Group (1 mentions) Il7ra mice, by Jackson ImmunoResearch (1 mentions) C57bl 6, by Jackson ImmunoResearch (1 mentions) Balb cj, by Jackson ImmunoResearch (1 mentions) Bromelain, by Merck Group (1 mentions)

2 protocols using ox40l ik 1

Immune Cell Phenotyping Antibody Panel

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Antibodies to human CD3 (UCHT1), CD4 (SK3), CD8 (SK1), CD11c (B-ly6), CD19 (HIB19), CD80 (L307.4), CD86 (IT2.2), CRTH2 (BM16), GTAT-3 (L50-823), IL-13 (JES10-5A2), IFN-γ (B27), Lineage cocktail 1, OX40L (IK-1) and TNF (MAb11) were obtained from BD (Franklin Lakes, NJ). Anti-human CD40 (MAB89) antibody was purchased from Beckman Coulter (Brea, CA). Anti-human CD1c (L161) and IL-4 (MP4-25D2) were from BioLegend (San Diego, CA). Anti-human HLA-DR (LN3) and IL-10 (JES3.9D7) were from eBioscience (San Diego, CA). Poly I:C was from Invivogen (San Diego, CA). Human CD14 (Tuk4) and CD45 (HI30) antibodies were from Life Technologies (Carlsbad, CA). Anti-human CD303 (AC144) and CD141 (AD5-14H12) antibodies were from Miltenyi Biotec (Auburn, CA). Recombinant human TSLP was from R&D Systems (Minneapolis, MN). Curdlan, PMA and ionomycin were purchased from Sigma-Aldrich (St. Louis, MO). Trivalent live-attenuated influenza (LAIV) vaccine FluMist® (MedImmune, Gaithersburg, MD) was obtained from the hospital pharmacy.

Yu C.I., Becker C., Metang P., Marches F., Wang Y., Toshiyuki H., Banchereau J., Merad M, & Palucka K. (2014). Human CD141+ DCs induce CD4+ T cells to produce type 2 cytokines. Journal of immunology (Baltimore, Md. : 1950), 193(9), 4335-4343.

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Murine Allergic Inflammation Study

Cited 1 time

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BALB/cJ, C57BL/6, Il4^−/− and Il7ra^-/- mice were from the Jackson Laboratory. Il5^−/− mice were from Dr. James Lee (Mayo Clinic Arizona, AZ). Female mice ages 6-12 weeks were used in all experiments. Antibodies to CD3 (145-2C11), CD25 (PC61; 7D4), CD44 (IM7), CD14 (M5E2), CD16/CD32 (2.4G2), CD45R/B220 (RA3-6B2), ICOS (7E.17G9), CD28 (37.51), IL-4Rα (mIL4R-M1), OX40 (ACT35), and OX40L (ik-1) were from BD Biosciences. Anti-OX40L mAb (RM134L) and polyclonal anti-OX40L Ab were from eBioscience and R&D Systems, respectively. Anti-ST2 mAb (97203) was from R&D Systems. Bromelain was from Sigma-Aldrich. Endotoxin-free ovalbumin (OVA) was prepared as described previously (6 (link)).

Drake L.Y., Iijima K, & Kita H. (2014). GROUP 2 INNATE LYMPHOID CELLS AND CD4+ T CELLS COOPERATE TO MEDIATE TYPE 2 IMMUNE RESPONSE IN MICE. Allergy, 69(10), 1300-1307.

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