Tabersonine

Monoindole alkaloid standards, such as catharanthine, tabersonine, and vindoline, as well as other chemicals, such as ammonium acetate, triethylamine, driselase, and sucrose, were purchased from Sigma-Aldrich (Missouri, USA). Bisindole alkaloid standards like vinblastine and vincristine were purchased from Cayman Chemicals (Michigan, USA). Acetonitrile and methanol were all LCMS grade and purchased from Merck (Darmstadt, Germany). Water was treated in a Milli-Q (Millipore, USA) water purification system. The other chemicals used for growth and elicitation studies, such as Gamborg B5 medium, 2,4-dichlorophenoxyacetic acid (2,4-D), jasmonate (JA), and methyl jasmonate (MeJA), were purchased from Duchefa Biochemie (Haarlem, Netherlands). The dye to stain for cell viability, fluorescein diacetate (FDA), was purchased from Merck Chemicals, Germany; the fluorochrome for mitochondria, MitoTracker Red FM, was purchased from Thermo Fisher Scientific Inc., Waltham, MA, USA.