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Tim 4 mice rbrc04895

Manufactured by RIKEN BioResource Center
Sourced in Japan

The Tim-4−/− mice (RBRC04895) are a genetically modified mouse strain developed at RIKEN BioResource Center. These mice have a targeted deletion of the Tim-4 gene, which encodes a receptor involved in the clearance of apoptotic cells. The core function of this mouse model is to study the role of Tim-4 in immune responses and the regulation of cell death processes.

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3 protocols using tim 4 mice rbrc04895

1

Tim-4 Knockout Mice in Research

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Tim-4−/− mice (RBRC04895) were obtained from Riken BioResource Center (Japan) and C57BL/6 mice were purchased from Taconic bioscience. Mice, 8–10-weeks old, were used regardless of sex in the study. For mouse studies, no statistical methods were used for sample estimate, no randomization was used, and no blinding was done. All experiments using mice were approved by the animal care and ethics committees of the Gwangju institute of science and technology (GIST) in accordance with the national institutes of health guide for the care and use of laboratory animals.
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2

Genetic Knockout Mice for Research

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Tim-4-/- mice (RBRC04895) were obtained from Riken BioResource Center (Japan), Mertk-/- mice (011122) were purchased from Jackson Laboratories (Bar Harbor, USA). All experiments using mice were approved by the animal care and ethics committees (LARC) of the Gwangju institute of science and technology (GIST) in accordance with the national institutes of health guide for the care and use of laboratory animals.
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3

Mouse Genetic Models for Immunology

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C57BL/6 were purchased from Taconic bioscience. Tim-4/ mice (RBRC04895) were obtained from Riken BioResource Center (Tsukuba, Japan). Mertk/ and Ccr2RFP mice were purchased from Jackson Laboratory, USA. Mcp-1/ mice were a generous gift from SungHoon Back at University of Ulsan. All mice were maintained and housed in equipped animal facility with temperature at 20–25 °C and humidity at 30–70%, under the same dark/light cycle (12:12). All experiments using mice were approved by the animal care and ethics committees of GIST in accordance with the national institutes of health guide for the care and use of laboratory animals.
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