To derive the central (aortic) arterial waveform, a validated system (SphygmoCorTM System; AtCor Medical, Sydney, Australia) was applied [5 (link), 7 (link), 20 (link)] by recording radial artery waveforms from the radial artery at the wrist, using high-fidelity applanation tonometer (Millar Instruments, Houston, Tex.) [5 (link), 6 (link), 20 (link)]. Corresponding central (aortic) waveforms were then automatically generated from the radial artery waveform by a validated transfer function [5 (link), 7 (link)]. This allows obtainment of the following parameters: central systolic pressure, central pulse pressure, central augmentation pressure, central augmentation index (cAIx), cAIx normalized to a heart rate of 75 beats per minute (cAIx@75), pulse pressure amplification, as well as forward and backward reflected wave amplitude.
Sphygmocortm system
Manufactured by AtCor Medical
Sourced in Australia
The SphygmoCor™ System is a non-invasive device that measures central blood pressure and arterial stiffness. It uses a specialized sensor to capture the pressure waveform at the radial artery, which is then used to derive central aortic pressure and other hemodynamic parameters.
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Lab products found in correlation
2 protocols using sphygmocortm system
1
Deriving Central Arterial Waveform
2
Hemodynamic Marker Evaluation using SphygmoCor
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Central hemodynamic markers were evaluated using a SphygmoCor TM system (AtCor Medical Pty Ltd, Sydney, Australia), which employs the principle of applanation tonometry, as previously described [18] . In brief, from radial artery recordings, central pressure was derived with the use of a generalized transfer function, which is an accurate estimate of the central pressure waveform. Waveforms of radial pressure were calibrated according to mean arterial pressure and diastolic blood pressure measured in the brachial artery. The AP is the pressure added to the incident wave by the returning reflected wave and represents the aortic blood pressure that the left ventricle must overcome during systole. AIx was calculated as the AP divided by the cPP and was expressed as a percentage.
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