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Pet ct discovery scanner

Manufactured by GE Healthcare

The PET/CT Discovery scanner is a medical imaging device that combines positron emission tomography (PET) and computed tomography (CT) imaging technologies. It is designed to provide detailed information about the structure and function of the body, which can be used for a variety of medical applications.

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2 protocols using pet ct discovery scanner

1

Whole-Body 18F-FDG PET/CT Imaging Protocol

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A whole-body PET/CT scan was performed from head to thigh, 60 min after intravenous administration of approximately 370 MBq (± 10%) of 18F-FDG on a PET/CT Discovery scanner (GE Healthcare Bio-Sciences Corp.). The patient was placed in the supine position, with the same immobilization system as in the radiotherapy treatment delivery. Other parameters included a 70 cm axial FOV, a 218 × 218 matrix. Data was acquired in a 3-D mode. The pixel spacing was 5.47 mm with a slice thickness of 3.27 mm. The spatial resolution varied from 3.99 mm to 4.56 mm. PET images were corrected using the specific software of the equipment for attenuation, scatter, decay, dead time, random coincidences, and slice sensitivity.
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2

Quantitative PiB-PET Imaging of Brain Amyloid Burden

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Carbon-11 based Pittsburgh Compound-B for positron emission tomography (PiB-PET) based estimation of individual brain Aβ load (Mathis et al., 2003 (link); Klunk et al., 2004 (link); Solbach et al., 2005 (link)) was performed as reported earlier by our group at the PET Center of the Division of Nuclear Medicine, Zürich University Hospital utilizing a GE PET/CT Discovery scanner (Steininger et al., 2014 (link)). In brief, an individual dose of 350 MBq of (11)carbon-labeled PiB was injected into the cubital vein. Images were corrected for attenuation using a low-dose CT. Standard quantitative filtered back projection algorithm including necessary corrections was applied.
Cerebral amyloid deposition values were extracted using a standard routine as implemented in PMOD Brain Tool software-package (PNEURO, Version 3.4, PMOD Technologies Ltd, Zürich, Switzerland). Late frame (minutes 50–70) values were standardized by the cerebellar gray matter value, resulting in 3D-volumes of PiB-PET retention (matrix dimensions: 128 × 128 × 47, voxel size: 2.34 × 2.34 × 3.27 mm).
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