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Aloperine

Manufactured by Merck Group
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Aloperine is a laboratory equipment product manufactured by Merck Group. It is a device used for the analysis and measurement of various chemical and biological samples. The core function of Aloperine is to provide accurate and reliable data for research and testing purposes.

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Lab products found in correlation

Nocodazole, by Merck Group (1 mentions) Dynasore, by Bio-Techne (1 mentions) Cytochalasin d, by Thermo Fisher Scientific (1 mentions)

2 protocols using aloperine

1

Aloperine and Microtubule Disruption

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Aloperine and nocodazole were purchased from Sigma-Aldrich. Alop1 denotes HPLC purified Aloperine to ensure the purity of the compound is greater than 95%. Dynasore was purchased from Tocris Bioscience. Cytochalasin D was purchased from Invitrogen.
Ho M.H., Huang L., Goodwin J.S., Dong X., Chen C.H, & Xie H. (2016). Two Small Molecules Block Oral Epithelial Cell Invasion by Porphyromons gingivalis. PLoS ONE, 11(2), e0149618.
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2

SARS-CoV-2 Spike Protein Inhibition Assay

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293T-ACE2 cells were kindly provided by Integral Molecular, PA and maintained in DMEM supplements with 10% FBS and 0.5 µg/mL of puromycin. Monoclonal antibody DH1047, and spike-pseudotyped viruses correlated to D614G, Delta, Omicrons including BA.1, BA.2, and BA.4/BA.5 were kindly provided by Dr. David Montefiori of Duke University. Aloperine was purchased from Sigma-Aldrich (Cat. # 546704, St. Louis, MO, USA). E64D was purchased from Selleck Chemicals (Cat. # S7393, Houston, TX, USA).
Huang L., Zhu L., Xie H., Goodwin J.S., Rana T., Xie L, & Chen C.H. (2022). Quinolizidines as Novel SARS-CoV-2 Entry Inhibitors. International Journal of Molecular Sciences, 23(17), 9659.
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