Multi channel knee coil

All imaging was performed using a Siemens 3-T Verio scanner with a multi-channel knee coil at the Wilford Hall Ambulatory Surgical Center, 59th Medical Wing, Joint Base San Antonio-Lackland AFB, TX. A human knee coil (inner diameter ~ 180 mm) provided an excellent coverage (field of view ~200 mm) for the brain and a comfortable fit for the animals placed in prone position. It provided a better signal-to-noise ratio (SNR) than volumetric coils for human brain imaging, however, SNR may likely be improved by the use of custom RF coils optimized for miniature pig anatomy. General anesthesia in the form of isoflurane was administered with an MRI-compatible machine for the 3-h scan duration. Metabolic and fluid status was continuously monitored and no subjects displayed signs of distress. Pigs were imaged in the prone position.

All imaging was performed using a Siemens 3-Tesla Verio scanner with a multi-channel knee coil at the Wilford Hall Ambulatory Surgical Center, 59^th Medical Wing, Joint Base San Antonio-Lackland AFB, TX. A human knee coil (inner diameter ~ 180 mm) provided excellent coverage (field of view ~ 200 mm) for the brain and a comfortable fit for the animals placed in the prone position. General anesthesia in the form of isoflurane was administered with an MRIcompatible machine for the 3-hour scan duration. Metabolic and fluid status was continuously monitored, and no subjects displayed signs of distress.