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Rmp1 14 or

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The RMP1-14 is a laboratory equipment used for the study of cellular and molecular biology. It is a multi-purpose instrument that performs various functions including cell culture, sample preparation, and analysis. The core function of the RMP1-14 is to provide a controlled environment for the cultivation and manipulation of cells.

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Lab products found in correlation

Be0098, by BioXCell (2 mentions) Isotype, by BioXCell (2 mentions) Igg2a isotype ctrl, by BioXCell (2 mentions) Balb c mice, by Charles River Laboratories (2 mentions)

2 protocols using rmp1 14 or

1

Combination Therapy for Tumor Regression

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3x105 CT26 RTT cells were injected subcutaneously into the right flank of female 6-8-week-old Balb/c mice (Charles River). Animals were irradiated under anaesthesia with Hypnorm/Hypnovel (Fentanyl-Fluanisone/Midazolam), administered i.p. Irradiation was performed on day 14 using an AGO 250kV X-ray machine (AGO, Reading, UK). Radiation dose (9Gy) was measured using a Farmer Chamber and Unidos-E dosimeter. FLT3L administration was initiated on day 7 and administered in 10 consecutive doses of 30 μg i.p. (BE0098 or Isotype, BioXCell in PBS). 100 μg anti-PD-1 (RMP1-14 or IgG2a Isotype CTRL, BioXCell) were administered on day 15, 18, 21 and 24. Body weight and tumour growth were measured twice weekly and tumour volumes calculated as: length x width x height (mm) x 0.5236.
Haas L., Elewaut A., Gerard C.L., Umkehrer C., Leiendecker L., Pedersen M., Krecioch I., Hoffmann D., Novatchkova M., Kuttke M., Neumann T., de Silva I.P., Witthock H., Cuendet M.A., Carotta S., Harrington K.J., Zuber J., Scolyer R.A., Long G.V., Wilmott J.S., Michielin O., Vanharanta S., Wiesner T, & Obenauf A.C. (2021). Acquired resistance to anti-MAPK targeted therapy confers an immune-evasive tumour microenvironment and cross-resistance to immunotherapy in melanoma. Nature cancer, 2(7), 693-708.
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2

Combination Therapy for Tumor Regression

Check if the same lab product or an alternative is used in the 5 most similar protocols
3x105 CT26 RTT cells were injected subcutaneously into the right flank of female 6-8-week-old Balb/c mice (Charles River). Animals were irradiated under anaesthesia with Hypnorm/Hypnovel (Fentanyl-Fluanisone/Midazolam), administered i.p. Irradiation was performed on day 14 using an AGO 250kV X-ray machine (AGO, Reading, UK). Radiation dose (9Gy) was measured using a Farmer Chamber and Unidos-E dosimeter. FLT3L administration was initiated on day 7 and administered in 10 consecutive doses of 30 μg i.p. (BE0098 or Isotype, BioXCell in PBS). 100 μg anti-PD-1 (RMP1-14 or IgG2a Isotype CTRL, BioXCell) were administered on day 15, 18, 21 and 24. Body weight and tumour growth were measured twice weekly and tumour volumes calculated as: length x width x height (mm) x 0.5236.
Haas L., Elewaut A., Gerard C.L., Umkehrer C., Leiendecker L., Pedersen M., Krecioch I., Hoffmann D., Novatchkova M., Kuttke M., Neumann T., de Silva I.P., Witthock H., Cuendet M.A., Carotta S., Harrington K.J., Zuber J., Scolyer R.A., Long G.V., Wilmott J.S., Michielin O., Vanharanta S., Wiesner T, & Obenauf A.C. (2021). Acquired resistance to anti-MAPK targeted therapy confers an immune-evasive tumour microenvironment and cross-resistance to immunotherapy in melanoma. Nature cancer, 2(7), 693-708.
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