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Elecsys anti hbs 2 assay

Manufactured by Roche
Sourced in Germany

The Elecsys anti-HBs II assay is an automated in vitro diagnostic test used to quantitatively determine the presence and level of antibodies to the hepatitis B surface antigen (anti-HBs) in human serum and plasma samples. The assay is designed for use on Roche's Elecsys and cobas e immunoassay analyzers.

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2 protocols using elecsys anti hbs 2 assay

1

Hepatitis B Screening in Young Patients

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Patients who applied to different outpatient clinics in the province between April 2017 and
June 2018 and who were born in 1998 or after were evaluated retrospectively. Patients who
were screened for HBsAg and anti-HBs for various reasons, such as pre-operative or school
enrolment tests, were included in this study. The data regarding HBsAg and anti-HBs was
obtained from the hospital information management system.
The Elecsys HBsAg II assay (Roche, Mannheim, Germany) and the Elecsys anti-HBs II assay
(Roche, Mannheim, Germany) were evaluated by patients' tests and using the ELISA technique.
Patients with anti-HBs levels higher than 10 IU/mL were considered positive.
They were divided into four groups according to their ages, 0-5, 6-10, 11-15 and 16-20.
HBsAg and anti-HBs positivity rates, HBsAg positive patients' genders and ages, and
positivity rate by age groups of anti-HBs patients were investigated; groups were compared
with each other.
The Ethics Committee of İstanbul Medipol University approved the study on November 11,
2022, with the decision number E-10840098-772.02-6792.
Statistical AnalysisThe statistical analyses were performed using the Statistical Package for Social Sciences
(SPSS) 22.0 (IBM Corp., Armonk, NY, USA). Pearson's chi-square test was used to compare the
differences in the categorical variables among the groups.
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2

Serum Anti-HBsAg Quantification

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Plasma samples were sent to a routine medical diagnostic lab (Labors.at, Vienna, Austria) for determination of reference values for anti-HBsAg antibody titer (mIU/mL). The reference lab used Elecsys Anti-HBs II assay (Roche 05894816) on Roche cobas 6000 (e601 module).
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