Flex coil

Manufactured by Siemens

Sourced in Germany

The Flex Coil is a versatile lab equipment product designed to provide a flexible and adaptable solution for various experimental setups. The core function of the Flex Coil is to generate a controlled electromagnetic field, which can be used for a range of applications in scientific research and laboratory settings.

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Lab products found in correlation

Verio 70 cm, by Siemens (3 mentions) Verio 70 cm open, by Siemens (2 mentions) Magnetom vida, by Siemens (1 mentions)

Close spelling variants of this product

18-channel body flex coil (2 citations) 4-channel flex coil (3 citations) 3T CP Large Flex Coil (2 citations) 550 g abdominal 4-Channel Siemens Flex Coil (2 citations) 4-channel Siemens large flex coil (2 citations)

7 protocols using flex coil

Fetal MRI Protocol for 3T Siemens Verio

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Fetal MR exams were performed with a Siemens Verio 70-cm open-bore 3-T scanner with a light-weight (~550 g) abdominal 4-Channel Siemens Flex Coil. The MRI examination lasted 45 min. Images were collected with the following parameters and computed SAR values: (i) localizer [repetition time/echo time (TR/TE), 20/4.2 ms; 10-mm thickness; SAR = 0.21]; (ii) T2 anatomical (TR/TE, 3500/140 ms; 3-mm slice thickness; repeated 4–6 times; SAR = 0.53); (iii) echo planar imaging (EPI) BOLD (TR/TE, 2000/30 ms; 180 frames; 4-mm slice thickness; axial; repeated twice; SAR = 0.3); (iv) susceptibility weighted imaging (SWI) (TR/TE, 30/21.2 ms; 4-mm slice thickness; SAR = 0.06).

Thomason M.E., Scheinost D., Manning J.H., Grove L.E., Hect J., Marshall N., Hernandez-Andrade E., Berman S., Pappas A., Yeo L., Hassan S.S., Constable R.T., Ment L.R, & Romero R. (2017). Weak functional connectivity in the human fetal brain prior to preterm birth. Scientific Reports, 7, 39286.

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Fetal MRI Neuroimaging Protocol

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Fetal MR exams were performed with a Siemens Verio 70-cm open-bore 3 Tesla scanner. An abdominal 4-Channel Siemens Flex Coil was placed around the maternal abdomen centered approximately at the fetal head. A T2 HASTE anatomical sequence (TR/ TE, 3500/ 140 ms; 3-mm slice thickness) was repeated six times, twice in each orientation. Echo planar imaging (EPI) BOLD (TR/ TE, 2000/ 30 ms; 180 frames; 4-mm slice thickness; axial) was performed for variable duration to accommodate readjustments to acquisition following fetal movement. The average number of BOLD fMRI time frames obtained per case was 349 (SD = 70). Specific absorption rates were extracted from fMRI scans for every subject.

Thomason M.E., Grove L.E., Lozon TA J.r., Vila A.M., Ye Y., Nye M.J., Manning J.H., Pappas A., Hernandez-Andrade E., Yeo L., Mody S., Berman S., Hassan S.S, & Romero R. (2014). Age-related increases in long-range connectivity in fetal functional neural connectivity networks in utero. Developmental Cognitive Neuroscience, 11, 96-104.

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Fetal Brain Functional Connectivity Imaging

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MRI scans were conducted on a Siemens Verio 70 cm open-bore 3T system using a lightweight (500 g) abdominal four-channel Siemens Flex Coil centered approximately at the fetal head. Resting-state fMRI data were acquired using a gradient echo planar imaging (EPI) sequence, TR/TE 2,000/30 ms, flip angle 80°, 360 frames, slice thickness 4 mm (axial), voxel size 3.4 ×3.4 × 4 mm³, 12 min. When possible, rs-fMRI scans were repeated to attain up to 24 min of functional resting-state data per participant. The average specific absorption rate (SAR), an estimated measure of radio-frequency energy, was 0.20 W/kg (SD = 0.07).

Norr M.E., Hect J.L., Lenniger C.J., Van den Heuvel M, & Thomason M.E. (2020). An examination of maternal prenatal BMI and human fetal brain development. Journal of child psychology and psychiatry, and allied disciplines, 62(4), 458-469.

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Fetal MRI Examination Protocol

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Fetal magnetic resonance exams were performed with a Siemens Verio 70-cm open-bore 3-Tesla scanner with a lightweight abdominal Siemens Flex Coil. The MRI examination lasted 45 min. Images were collected with the following parameters and system-derived estimates of specific absorption rate: echo planar imaging blood oxygen level dependent, response time/echo time 2000/30 ms, minimum 180 frames, axial 4-mm slice, specific absorption rate = 0.22 (SD = 0.08). For the final sample of 96 cases included in all analyses, frame count, after excluding high motion frames, was range = 90 to 330, M = 155, SD = 48. Fetal MRI motion was included as covariate in all subsequent analyses for included participants.

THOMASON M.E., HECT J., WALLER R., MANNING J.H., STACKS A.M., BEEGHLY M., BOEVE J.L., WONG K., VAN DEN HEUVEL M.I., HERNANDEZ-ANDRADE E., HASSAN S.S, & ROMERO R. (2018). Prenatal neural origins of infant motor development: Associations between fetal brain and infant motor development. Development and psychopathology, 30(3), 763-772.

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3T MRI Acquisition Using Flex Coil

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We collected all imaging data with a 3T MRI scanner (Magnetom Vida, Siemens) at the Imaging Neuroscience Center at the University of Utah. We placed a Siemens flex coil (size: small) over the anterior and superior aspects of the subject’s head to maximize the signal-to-noise ratio of the acquired signals.

Riis T., Feldman D., Losser A., Mickey B, & Kubanek J. (2024). Device for multifocal delivery of ultrasound into deep brain regions in humans. IEEE transactions on bio-medical engineering, 71(2), 660-668.

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Fetal Brain Functional Imaging

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A 3T Siemens Verio 70 cm open-bore system with a 550 g abdominal four-channel Siemens Flex coil was used to collected fetal resting state functional MRI data. For each participant, 360 axial frames (12 min) of EPI-BOLD data were collected with the following scan sequence parameters: TR = 2000 ms; TE = 30 ms; flip-angle: 80 degrees, slice-gap: none; voxel-size: 3.4 mm x 3.4 mm x 4 mm; matrix-size: 96 × 96 × 25 voxels.

Hendrix C.L., Srinivasan H., Feliciano I., Carré J.M, & Thomason M.E. (2022). Fetal Hippocampal Connectivity Shows Dissociable Associations with Maternal Cortisol and Self-Reported Distress during Pregnancy. Life, 12(7), 943.

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Fetal Resting-State fMRI Acquisition

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Fetal functional brain imaging was performed with a Siemens Verio 70-cm open-bore 3-Tesla scanner with a lightweight abdominal Siemens Flex Coil (Siemens, Munich, Germany). Resting-state fMRI data were acquired using a gradient echo planar imaging sequence: TR/TE 2000/30 milliseconds, flip angle 80°, 360 frames, axial 4-mm slice thickness, voxel size 3.4 × 3.4 × 4 mm³, repeated twice. Between 12 and 24 minutes of fetal resting-state fMRI data were collected per participant. The average system derived estimates for specific absorption rate was 0.22 watts per kilogram (SD = 0.06).

van den Heuvel M.I., Monk C., Hendrix C.L., Hect J., Lee S., Feng T, & Thomason M.E. (2023). Intergenerational Transmission of Maternal Childhood Maltreatment Prior to Birth: Effects on Human Fetal Amygdala Functional Connectivity. Journal of the American Academy of Child and Adolescent Psychiatry, 62(10), 1134-1146.

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