The T2-weighted MRI of the mice were performed with a clinical Magnetom Trio Tim MRI spectrometer (3.0 Tesla, Siemens Prisma, Germany) using optimized sequences of 3000 ms repetition time, 80 ms echo time, 1.0 mm slice thickness, 1.0 mm slice space thickness and 30 × 96 mm field of view. Prior to the SPION injection, MRI was first performed on all mice as the baseline references. SPION solutions including PDL-SPION, C-pHLIP-SPION and N-pHLIP-SPION (100 μL each) were then intravenously injected at 5 mg Fe per kg body weight (3 mice per group). MRI was performed at 0, 2, 4 and 24 h post iv injection. The resulting MR images were processed with provided Syngo Fastview software (Siemens, Germany).
Syngo fastview software
Manufactured by Siemens
Sourced in Germany
Syngo fastView software is a medical imaging software developed by Siemens. It is designed to provide fast and efficient visualization of medical images, allowing healthcare professionals to quickly access and analyze patient data.
Automatically generated - may contain errors
5 protocols using syngo fastview software
1
In Vivo MRI Tracking of SPION
2
Neuroimaging of Anesthetized Monkey Brains
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Neuroimaging analysis was first conducted to identify gross anatomical abnormalities in the whole brains of monkeys. High-resolution images were acquired using a Siemens Skyra 3.0 T (Siemens Healthcare GMbH, Germany). Before scanning, the anesthetized monkeys were placed onto the coil bed with heads fixed. Body temperature was maintained using padding for thermal insulation. During the session, whole brain volumes were obtained, and the horizontal plane was reconstructed offline using syngo fastView software (Siemens AG, Germany).
3
Measuring Tumor Volume Using MRI
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After rats were anesthetized and fixed in a 7-cm small animal coil (MR750 3.0 T, GE, USA), coronal and sagittal MRI scans were performed. The scanning parameters were set as follows: layer thickness, 2 mm; layer spacing, 2 mm; and FOV, 120 mm × 120 mm. For T1WI, a 0Ax T1-FSE sequence was used, where the TR/TE was 6.072 ms/597 ms; for T2WI, a 0Ax T2-FSE sequence was used, where the TR/TE was 123.9 ms/5000 ms. The MRI analysis and tumor volume calculations were performed using syngo fastView software (Siemens, Germany). The image of the largest level of the tumor was selected to measure the volume. The following formula (mm3) was used for the calculation: length × width × height × (π/6).
4
Analyzing Tibial Cartilage Changes via MRI
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Magnetic resonance images were analyzed using Syngo FastView software (Siemens©, AG, Berlin and Munich 2004–2008). The proximal tibial joint cartilage was identified and then analyzed for discontinuity and intensity changes (Fig. 2 ). Also, the T1 value of the cartilage (Fig. 3 ) was measured, seeking changes above 25 % using Siswin software version 0.9 (Steffen Ringgaard© 2008).![]()
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Magnetic resonance images (T1 and T2), study A. After the procedure, the physis can be observed to be disrupted (arrows). The articular cartilage above the epiphysiodesis looks continuous and homogenous
Water content calculation. An area of interest was established around the joint cartilage (yellow) and a mean T1 value was obtained. This allows calculating the water content of this area
5
High-Resolution Knee MRI Imaging
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The MRI scanning was performed using a 3T whole body MRI scanner (Magnetom Skyra, Siemens; Erlangen, Germany). The following sequences were used: pd_tse_sag_FS_hi-res and pd_tse_cor_FS_hi-res (Voxel size of 0.3 x 0.3 x 2.0 mm; field of view [FOV] read of 140 mm; FOV phase of 100%; slice thickness of 2 mm; repetition time of 2000 ms; time to echo of 13 ms). Syngo fastView software (Siemens Healthineers; Erlangen, Germany) was used in the MRI scan analysis.
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