1.5t gyroscan intera system

Diffusion tensor imaging data were acquired using a Synergy-L SENSE head coil on a 1.5T Gyroscan Intera system (Philips, Best, The Netherlands) equipped with single-shot echo-planar imaging. For each of the 32 non-collinear diffusion sensitizing gradients, 67 contiguous slices were acquired parallel to the anterior commissure–posterior commissure line. Imaging parameters were as follows: acquisition matrix = 96 × 96, reconstructed matrix = 192 × 192 matrix, field of view = 240 × 240 mm², TR = 10,398 ms, TE = 72 ms, parallel imaging reduction factor (SENSE factor) = 2, EPI factor = 59 and b = 1000 s/mm², NEX = 1, slice gap = 0, and slice thickness 2.5 mm.

DTI data were obtained by using a Synergy-L sensitivity encoding six-channel head coil on a 1.5T GyroscanIntera system (Philips, Best, The Netherlands) equipped with single-shot echo-planar imaging. For each of the 32 non-collinear diffusion-sensitizing gradients, we acquired 67 contiguous sections parallel to the anterior/posterior commissure line. Imaging parameters were as follows: acquisition matrix = 96 × 96, reconstructed to matrix = 128 × 128, FOV = 221 mm × 221 mm, TR = 10,726 ms, TE = 76 ms, parallel imaging reduction factor (SENSE factor) = 2, EPI factor = 49, b = 1000 s/mm², NEX = 1, and a section thickness of 2.3 mm (acquired voxel size, 1.73 mm × 1.73 mm × 2.3 mm). The Oxford Center for Functional Magnetic Resonance Imaging of the Brain (FMRIB) Software Library¹ was used for correction of head motion effect and image distortion due to eddy currents. For analysis of the CST, the first ROI was placed on the CST portion of the ponto-medullary junction (blue color) and the second ROI on the CST portion of the anterior portion of the midpons (blue color). We reconstructed CST using DTI-Studio software with a 0.2 of fractional anisotropy and tract turning-angle of <60° (CMRM, Johns Hopkins Medical Institute, Baltimore, MD, USA).