Endoplasmic reticulum stress inducers, including thapsigargin; TG (T9033) and tunicamycin; TM (T7765), cisplatin (C2210000) and the nitric oxide (NO) scavengers such as carboxy-PTIO potassium salt; cPTIO (C221) and Sodium diethyldithiocarbamate trihydrate; Cupral (D3506) were purchased from Sigma-Aldrich (St. Louis, MO, USA). The DNA methyltransferase inhibitor; decitabine (S1200) was purchased from Selleck Chemicals (Houston, TX, USA).
Carboxy ptio potassium salt
Manufactured by Merck Group
Sourced in United States
Carboxy-PTIO potassium salt is a chemical compound used in various laboratory applications. It is a stable and water-soluble spin trap that can be used to detect and study free radicals and other reactive oxygen species. The core function of this product is to serve as a tool for researchers and scientists in their investigations.
Automatically generated - may contain errors
Lab products found in correlation
Decitabine, by Selleck Chemicals (2 mentions)
Tg t9033, by Merck Group (1 mentions)
S nitroso n acetyl dl penicillamine, by Merck Group (1 mentions)
Diethylamine nonoate sodium salt hydrate, by Merck Group (1 mentions)
S nitrosoglutathione, by Merck Group (1 mentions)
Cisplatin, by Merck Group (1 mentions)
Thapsigargin, by Merck Group (1 mentions)
Tunicamycin, by Merck Group (1 mentions)
3 protocols using carboxy ptio potassium salt
1
Endoplasmic Reticulum Stress Inducers and Inhibitors
2
Characterization of NO Donor Kinetics
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
NO donors with different half-lives in pH 7.4 buffer tested in this study are listed in Table 1 . Sodium nitroprusside (SNP), S-nitroso-N-acetyl-DL-penicillamine (SNAP), S-nitrosoglutathione (GSNO), MAHMA NONOate (NOC-9), PROLI NONOate and Spermine NONOate (S150), diethylamine NONOate sodium salt hydrate (DEA NONOate) and carboxy-PTIO potassium salt (PTIO) were purchased from Sigma Aldrich, UK. SNP and RSNOs stock solutions were prepared in phosphate saline buffer (pH 7.4), with SNP prepared and kept in dark. NONOates stock solutions were prepared in 0.01 M NaOH. All stock solutions were filter sterilized and diluted into fresh M9 media on ice. During preparation procedures, all solutions were kept on ice before use and SNP was kept in the dark. All treatments were conducted at 37°C, with SNP exposed to light.
NO donors tested in this study and their half-lives at 37°C, pH ~ 7.4
| SNP | < 2 mins |
| SNAP | 6 h |
| GSNO | 1–3 h |
| PROLI NONOate | 1.8 s |
| MAHMA NONOate | 1 min |
| Spermine NONOate (S150) | 39 min |
| DEA-NONOate | 2 min |
3
Endoplasmic Reticulum Stress Inducers
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
Endoplasmic reticulum stress inducers, including thapsigargin and tunicamycin, cisplatin and the nitric oxide (NO) scavengers such as carboxy-PTIO potassium salt (cPTIO) and Sodium diethyldithiocarbamate trihydrate (Cupral) were purchased from Sigma-Aldrich (St. Louis, MO, USA). The DNA methyltransferase inhibitor; decitabine was purchased from Selleck Chemicals (Houston, TX, USA).
About PubCompare
Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.
We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.
However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.
Ready to get started?
Sign up for free.
Registration takes 20 seconds.
Available from any computer
No download required
Revolutionizing how scientists
search and build protocols!