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Platinum 2 acetylacetonate pt acac 2

Manufactured by Strem Chemicals

Platinum(II)acetylacetonate (Pt(acac)2) is a platinum-based compound used in various chemical applications. It is a crystalline solid with the chemical formula C10H14O2Pt. The compound can be utilized in various research and industrial settings.

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2 protocols using platinum 2 acetylacetonate pt acac 2

1

Synthesis of cRGDfC-Labeled Nanoparticles

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The
integrin αvβ3 targeting peptide
cyclo (Arg-Gly-Asp-d-Phe-Cys)
(cRGDfC) was purchased from Peptides International, Inc. (Louisville,
KY). The p-SCN-Bn-NOTA was purchased from Macrocyclics, Inc. Hydrogen
tetrachloroaurate(III) hydrate (HAuCl4) and platinum(II)
acetylacetonate (Pt(acac)2) was ordered from Strem Chemicals,
Inc. N-Hydroxysuccinimide (NHS), N-hydroxysulfosuccinimide (sulfo-NHS), succinimidyl 4-(N-maleimidomethyl) cyclohexane-1-carboxylate (sulfo-SMCC), and 1-ethyl-3-(3-dimethylaminopropyl)
carbodiimide, hydrochloride (EDC) were purchased from Thermo Fisher
Scientific. All other chemicals were purchased from Sigma-Aldrich.
Other solvents and chemicals were used as received. All buffers and
media were purchased from Invitrogen Corp. Deionized water was obtained
from a Millipore Milli-DI Water Purification system. The dialysis
membrane tubing (MWCO: 12,000–14,000, and 100,000) were purchased
from Spectrum laboratories.
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2

Synthesis of Gold and Platinum Complexes

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Hydrogen tetrachloroaurate (III) hydrate (HAuCl4) and platinum (II) acetylacetonate (Pt(acac)2) were ordered from Strem Chemicals, Inc. N-hydroxysuccinimide (NHS), N-hydroxysulfosuccinimide (sulfo-NHS), and 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide, hydrochloride (EDC) were purchased from Thermo Fisher Scientific. All other chemicals were purchased from Sigma-Aldrich. Triethylamine and dichloromethane (DCM) were distilled prior to use, and N, N’-dimethylformamide (DMF) was stored over molecular sieves. Other solvents and chemicals were used as received. Deionized water was obtained from a Millipore Milli-DI Water Purification system. The dialysis membrane tubing (MWCO: 12,000 ~ 14,000, and 100,000) were purchased from Spectrum laboratories.
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