integrin αvβ3 targeting peptide
cyclo (Arg-Gly-Asp-
(cRGDfC) was purchased from Peptides International, Inc. (Louisville,
KY). The p-SCN-Bn-NOTA was purchased from Macrocyclics, Inc. Hydrogen
tetrachloroaurate(III) hydrate (HAuCl4) and platinum(II)
acetylacetonate (Pt(acac)2) was ordered from Strem Chemicals,
Inc. N-Hydroxysuccinimide (NHS), N-hydroxysulfosuccinimide (sulfo-NHS), succinimidyl 4-(N-maleimidomethyl) cyclohexane-1-carboxylate (sulfo-SMCC), and 1-ethyl-3-(3-dimethylaminopropyl)
carbodiimide, hydrochloride (EDC) were purchased from Thermo Fisher
Scientific. All other chemicals were purchased from Sigma-Aldrich.
Other solvents and chemicals were used as received. All buffers and
media were purchased from Invitrogen Corp. Deionized water was obtained
from a Millipore Milli-DI Water Purification system. The dialysis
membrane tubing (MWCO: 12,000–14,000, and 100,000) were purchased
from Spectrum laboratories.