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Ox40 fc

Manufactured by Enzo Life Sciences
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OX40:Fc is a recombinant protein consisting of the extracellular domain of the human OX40 receptor (TNFRSF4) fused to the Fc region of human IgG1. OX40:Fc functions as a soluble receptor that can bind to OX40 ligand (TNFSF4), a member of the tumor necrosis factor superfamily expressed on activated T cells.

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Lab products found in correlation

Cd40 fc, by Enzo Life Sciences (2 mentions) Baffr fc, by Enzo Life Sciences (2 mentions) Cd154, by Enzo Life Sciences (2 mentions) Ox40l, by Enzo Life Sciences (2 mentions) Monoclonal anti human cd154 clone 40804, by R&D Systems (2 mentions) Tnf α, by Enzo Life Sciences (2 mentions) Cd40l, by Thermo Fisher Scientific (2 mentions) Tnf r1 fc, by Enzo Life Sciences (2 mentions)

2 protocols using ox40 fc

1

Recombinant Receptor-Ligand Interactions

Check if the same lab product or an alternative is used in the 5 most similar protocols
All chemicals and reagents used were obtained from Sigma-Aldrich (St. Louis, MO, USA) except as indicated. Recombinant receptors (CD40:Fc, OX40:Fc, BAFFR:Fc, and TNF-R1:Fc) and FLAG-tagged ligands (CD154, OX40L, BAFF, and TNF-α) were obtained from Enzo Life Sciences (San Diego, CA, USA). CD40L used in the thermal shift assay was from Peprotech (Rocky Hill, NJ, USA). The monoclonal anti-human CD154 (clone 40804) was obtained from R&D Systems (Minneapolis, MN, USA).
Bojadzic D., Chen J., Alcazar O, & Buchwald P. (2018). Design, Synthesis, and Evaluation of Novel Immunomodulatory Small Molecules Targeting the CD40–CD154 Costimulatory Protein-Protein Interaction. Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry, 23(5), 1153.
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2

Recombinant Receptor-Ligand Interactions

Check if the same lab product or an alternative is used in the 5 most similar protocols
All chemicals and reagents used were obtained from Sigma-Aldrich (St. Louis, MO, USA) except as indicated. Recombinant receptors (CD40:Fc, OX40:Fc, BAFFR:Fc, and TNF-R1:Fc) and FLAG-tagged ligands (CD154, OX40L, BAFF, and TNF-α) were obtained from Enzo Life Sciences (San Diego, CA, USA). CD40L used in the thermal shift assay was from Peprotech (Rocky Hill, NJ, USA). The monoclonal anti-human CD154 (clone 40804) was obtained from R&D Systems (Minneapolis, MN, USA).
Bojadzic D., Chen J., Alcazar O, & Buchwald P. (2018). Design, Synthesis, and Evaluation of Novel Immunomodulatory Small Molecules Targeting the CD40–CD154 Costimulatory Protein-Protein Interaction. Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry, 23(5), 1153.
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