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Nisoxetine hcl

Manufactured by Merck Group
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Nisoxetine HCl is a laboratory chemical compound used as a reference standard or analytical reagent. It is the hydrochloride salt of nisoxetine, a norepinephrine reuptake inhibitor. The core function of Nisoxetine HCl is to serve as a tool for researchers and analysts in various scientific applications, such as chemical analysis, drug development, and pharmacological studies.

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Lab products found in correlation

Reserpine, by Bio-Techne (1 mentions) Cocaine hcl, by Merck Group (1 mentions) Mazindol, by Lipomed (1 mentions) 3h dopamine, by PerkinElmer (1 mentions)

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Nisoxetine (5 citations)

2 protocols using nisoxetine hcl

1

Radioactive Noradrenaline Binding Assay

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Levo-[7-3H]-noradrenaline (specific activity = 20 Ci/mmol) was purchased from American Radio-labeled Chemicals (St. Louis, MO, USA). The following drugs were used: prazosin HCl (RBI), reserpine (Tocris Bioscience, Bristol, UK) nisoxetine HCl and cocaine HCl (Sigma-Aldrich, Budapest, Hungary). All other chemicals were obtained from Sigma-Aldrich (Budapest, Hungary).
Al-Khrasani M., Karadi D.A., Galambos A.R., Sperlagh B, & Vizi E.S. (2022). The Pharmacological Effects of Phenylephrine are Indirect, Mediated by Noradrenaline Release from the Cytoplasm. Neurochemical Research, 47(11), 3272-3284.
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2

Pharmacological Characterization of Novel Synthetic Cathinones and Amphetamines

Cited 1 time
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Mazindol, MDA HCl, MDMA HCl, MDPV HCl, methylone HCl, and fluoxetine HCl were purchased from Lipomed (Arlesheim, Switzerland). Nisoxetine HCl was obtained from Sigma Aldrich (Buchs, Switzerland). 3,4-Dihydroxyamphetamine (HHA) HCl, 3,4-dihydroxymethamphetamine (HHMA) fumarate, 4-hydroxy-3-methyoxyamphetamine (HMA) fumarate, and 4-hydroxy-3-methoxymethamphetamine (HMMA) HCl were synthesized and analysed for purity at the Research Triangle Institute (RTI, Durham, NC, USA) (Schindler et al., 2014 (link)). 3,4-Dihydroxymethcathinone (HHMC) HBr, 4-hydroxy-3-methyoxymethcathinone (HMMC) HCl, and 3,4-methylenedioxycathinone (MDC) HCl, were synthesized as described in (Ellefsen et al., 2015 ); 3,4-dihydroxypyrovalerone (HHPV) HBr and 4-hydroxy-3-methyoxypyrovalerone (HMPV) HCl were synthesized as described in (Anizan et al., 2014 (link)). All drugs were used as racemic mixtures. Radiolabeled [3H]norepinephrine (13.1 Ci/mmol) and [3H]dopamine (30.0 Ci/mmol) were attained from Perkin-Elmer (Schwerzenbach, Switzerland). Radiolabeled [3H]5-HT (80 Ci/mmol) was obtained from Anawa (Zurich, Switzerland).
Luethi D., Kolaczynska K.E., Walter M., Suzuki M., Rice K.C., Blough B.E., Hoener M.C., Baumann M.H, & Liechti M.E. (2019). Metabolites of the ring-substituted stimulants MDMA, methylone, and MDPV differentially affect human monoaminergic systems. Journal of psychopharmacology (Oxford, England), 33(7), 831-841.
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