129s8 svevnimrj

Male 129S1/SvlmJ, 129S4/SvJaeJ, 129S8/SvEvNimrJ, A/J, AKR/J, BALB/cJ, BTBRT < +>ltpr3 < tf>/J, C3H/HeJ, C57BL/6J, CBA/J, DBA/1J, DBA/2J, FVB/NJ, LP/J, MA/MyJ, NZB/BINJ, SJL/J, SM/J, & SWR/J mice were obtained from Jackson Laboratory (Bar Harbor, ME). 129S2/SvPasCrl were obtained from Charles River (Wilmington, MA). Individual strain characteristics can be found on https://mice.jax.org/ and https://www.criver.com/ (129S2). These mice were part of a larger project examining the influence of genetic background on sensitivity to drugs of abuse. All mice were 10–15 weeks of age for behavioral testing and tissue collection (n = 9–13 per strain). All mice were group-housed [with the exception of SJL/J, which were single-housed due to excessive social aggression characteristic of this strain; (43 (link))] with a 12-h light/dark cycle and unlimited access to food and water. All behavioral testing occurred between 8:00 A.M. and 5:00 P.M. All procedures were conducted in accordance with the NIH Guide for the Care and Use of Laboratory Animals and approved by the Penn State University IACUC Committee.

The subjects were adult (10–13 weeks at time of liver dissection), male mice of eight inbred mouse strains: 129S2/SvPasCrl, 129S4/SvJaeJ, 129S8/SvEvNimrJ, BTBR T+ Itpr3tf/J, C57BL/6J, MA/MyJ, NZB/BINJ and SM/J (n = 9 per treatment group per strain, all strains aside from 129S2/SvPasCrl purchased from Jackson Laboratory, Bar Harbor, ME, USA; 129S2/SvPasCrl purchased from Charles River, Wilmington, MA, USA). All mice were group-housed in the same colony room with a 12 h light/dark cycle and ad libitum access to food and water. All procedures were performed in accordance with the NIH Guide for the Care and Use of Laboratory Animals and were approved by the Pennsylvania State University IACUC committee.